TY - T1的梗死体积预测复苏长期残疾蛛网膜下腔出血(P06.253) JF -神经学乔-神经病学SP - P06.253 LP - P06.253六世- 78 - 1补充AU -尼尔·罗森博格AU -风暴Liebling AU -马修首页马斯河盟-安德鲁Naidech Y1 - 2012/04/26 UR - //www.ez-admanager.com/content/78/1_Supplement/P06.253.abstract N2 -目的:评估预测三个月结果动脉瘤性蛛网膜下腔出血患者(aSAH表示)在14天严重残疾。SAH后背景验证预测结果包括延迟脑缺血、年龄、神经功能评分的承认。复苏那些仍然所知甚少严重神经受伤在14天。因为病人之间的延迟缺血严重程度不同,其后果也应该有所不同。因此,我们假设脑梗死体积与这些患者的复苏。设计/方法:我们前瞻性地确定连续SAH病人和临床数据记录,包括脑梗死常规CT扫描获得的。我们定义严重的神经损伤在14天改良Rankin规模(夫人)4或5,NIH卒中标准≥8。夫人是前瞻性记录三个月(0 - 3夫人、功能独立,和夫人4 - 6,依赖或死亡)。梗死体积计算(AnalyzeDirect,梅奥诊所)的CT诊断。我们探讨的结果决定因素与物流和序数回归。结果:在14天,87名患者(平均年龄58.0±14.7年,37.5%的男性)有严重的神经损伤,63(71.6%)梗死灶。 Three-month outcomes were known in 79 (89.8%), 27 (30.7%) of whom were independent. Fourteen (16%) patients died, 7 from withdrawal of support. Age and infarct volume were associated with outcome, but transcranial Doppler velocity above 120 cm/s, symptomatic vasospasm, WFNS grade, and modified Fisher grade were not. In multivariate logistic regression, age (1.07 per year, 95%CI 1.02-1.1, P=0.002) and infarct volume (1.05 per mL, 95%CI 1.01-1.08, P=0.01) were associated with increased odds of 3-month dependence or death. Results were similar for ordinal regression.Conclusions: In patients with aSAH who remain severely neurologically injured at 14 days, recovery is possible and is associated with age and infarction volume. These data may aid in planning care.Disclosure: Dr. Rosenberg has nothing to disclose. Dr. Liebling has nothing to disclose. Dr. Maas has nothing to disclose. Dr. Naidech has received research support from Gaymar Inc.Thursday, April 26 2012, 07:30 am-12:00 pm ER -