TY -的T1 Alexythimia和道德判断多发性硬化症患者(P04.115) JF -神经学乔-神经病学SP - P04.115 LP - P04.115六世- 78 - 1补充AU - 首页Vladimiro Sinay AU -尼法昆盟Ezequiel Gleichgerrcht Y1 - 2012/04/25 UR - //www.ez-admanager.com/content/78/1_Supplement/P04.115.abstract N2 -目的:探讨情绪干扰对道德判断的影响在多发性硬化症患者。情绪处理干扰背景和社会认知赤字的关系已被广泛研究多发性硬化(MS)患者。然而,对情感问题对道德判断的影响,复杂的相互作用的一个认知过程,结果自动/情感过程和认知控制过程。设计/方法:30复发患者行/女士完成一连串的道德困境,客观场景(间接受害者受伤,因此给低情感特点)和个人场景(受害人直接造成损害,从而呈现高情感特点)。病人也完成了多伦多Alexythimia规模(TAS-20)。Results: When patients were grouped according to their TAS-20 total scores on whether they exhibited alexythimia (35.7%), borderline alexhytimia (28.6%), or no alexythimia (35.7%), the first group consistently considered it was more appropriate to kill one to save many than the other patient groups (p < .05 for both). A significant correlation was found between how appropriate it was to damage the victim in personal scenarios and the difficulty in identifying (r=.48, p=.01) and describing (r=.40, p=.03) emotions, as well as the TAS-20 total score (r=.51, p<.01). Said correlation was absent for impersonal scenarios.Conclusions: Impairments in identifying and describing emotions among patients with MS seem to have an impact on the way they judge moral dilemmas that present high emotional saliency. Our findings suggest there are shared neural networks feeding emotion and moral cognition which may be affected in a subgroup of MS patients.Disclosure: Dr. Sinay has received personal compensation for activities with Bayer, Biogen Idec, Teva Tuteur, Novartis, and Merck Serono. Dr. Sinay has received research support from Merck Serono and Teva Tuteur. Dr. Manes has nothing to disclose. Dr. Gleichgerrcht has nothing to disclose.Wednesday, April 25 2012, 07:30 am-12:00 pm ER -