TY -的T1 -非患病率和Pre-Motor症状患者的肌萎缩性脊髓侧索硬化症(P07.070) JF -神经学乔-神经病学SP - P07.070 LP - P07.070亚历山大六世- 80 - 7补充AU - Shtilbans AU -妮可首页Kassebaum盟蒙娜Shahbazi AU -戴尔兰格Y1 - 2013/02/12 UR - //www.ez-admanager.com/content/80/7_Supplement/P07.070.abstract N2 -目的:研究普遍存在的非症状患者的肌萎缩性脊髓侧索硬化症(ALS)使用新设计的筛选问卷。我们也试图识别症状,可能会出现之前的弱点。背景:很少有非机动车的报告文学在ALS患者的症状。这些症状从未被研究以系统的方式使用一个全面的筛选问卷,因此病人的访问期间可能会错过。也不知道如果第一个表现运动症状,或者可能有其他症状前几个月或几年的最明显的运动症状。设计/方法:这是一个横断面,回顾性研究中,我们调查了24 ALS患者和7控制弱点使用新设计的其他原因37-item self-completed筛查问卷。选择的问题是基于之前发表的文献和经验我们肌肉萎缩症协会的成员诊所。结果:非机动车从精神病症状,认知,锥体束外的和睡眠领域更普遍的ALS组相比,数量有限的控制。四24 ALS患者抱怨的尖叫,踢在睡眠中并没有指出在控制。三个4病人指出这个症状之前出现的弱点。 The most common symptoms in ALS group were muscle cramping and twitching (19 out of 24), while poor balance was most common symptom in both groups.CONCLUSIONS: Our study shows that non-motor symptoms in ALS patients are common and may occur before onset of weakness. Further studies are necessary to confirm this preliminary pilot data and to validate the used questionnaire as a useful screening tool. The knowledge of various domains involved in the disease would prevent failure to diagnose potentially co-morbid symptoms and improve individualized delivery of care.Disclosure: Dr. Shtilbans has nothing to disclose. Dr. Kassebaum has nothing to disclose. Dr. Shahbazi has nothing to disclose. Dr. Lange received financial support for research activities from CSL Behring, GlaxoSmithKline, and Cytokinetics.Thursday, March 21 2013, 2:00 pm-7:00 pm ER -