吴@article {Wu2045作者= {Bo和肖颖姚明和春燕Lei h·斯莱姆和明刘Magdy}, title ={扩大血管周的空间和小diffusion-weighted病变在脑内出血},体积={85},数量={23},页面= {2045 - 2052}= {2015},doi = {10.1212 / WNL。出版商0000000000002169}= {Wolters Kluwer健康,公司代表美国神经病学学会},文摘={目的:检查之间的联系扩大血管周的空间(EPVS)和小急性diffusion-w首页eighted成像的患病率和程度(驾车)病变(SA-DWIL)自发性幕上脑出血患者(我)。方法:我们进行了一项回顾性研究201例连续队列的自发性幕上的我脑MRI与醉酒驾车1月内的我开始。我们比较的临床和影像特征,包括EPVS、患者和没有SA-DWIL。我们使用了单变量和多变量逻辑回归分析来确定与SA-DWIL相关的变量。结果:小急性醉酒驾车病变中发现27.9 \ % (n = 56)的患者。脑室、蛛网膜下腔扩大我(p < = 0.001),高中枢semiovale(方案){\ textendash} EPVS \ (p < 0.001),高基底神经节{\ textendash} EPVS (p = 0.007),整体的白质hyperintensity程度(p = 0.018),最初我体积(p \ < 0.001),平均变化量平均动脉血压(δ=地图地图承认——最低的地图前MRI扫描)(p = 0.027)与SA-DWIL在单变量分析。在多变量逻辑回归分析,大的我卷(比值比(或)1.03;95 \ %可信区间[CI] 1.01 {\ textendash} 1.06;p = 0.006)和高CSO-EPVS(或12.56;95 \ % CI 4.40 {\ textendash} 35.85;p \ < 0.001)分别与有关SA-DWIL的存在。Conclusions: In our cohort, high EPVS, in particular CSO-EPVS, and larger hematoma volume emerged as independent predictors for SA-DWIL after ICH. Our findings might provide a new explanation for the pathophysiologic mechanisms predisposing to SA-DWIL after ICH.ADC=apparent diffusion coefficient; BG=basal ganglia; BP=blood pressure; CAA=cerebral amyloid angiopathy; CSO=centrum semiovale; DBP=diastolic blood pressure; DWI=diffusion-weighted imaging; DWM=deep white matter; EPVS=enlarged perivascular spaces; FLAIR=fluid-attenuated inversion recovery; GRE=gradient echo; ICH=intracerebral hemorrhage; IVH=intraventricular hemorrhage; MAP=mean arterial blood pressure; PVWM=periventricular white matter; ROI=region of interest; SA-DWIL=small acute lesions on diffusion-weighted imaging; SBP=systolic blood pressure; TE=echo time; TR=repetition time; WMH=white matter hyperintensity}, issn = {0028-3878}, URL = {//www.ez-admanager.com/content/85/23/2045}, eprint = {//www.ez-admanager.com/content/85/23/2045.full.pdf}, journal = {Neurology} }