RT期刊文章SR电子T1的进化创伤实质颅内血肿(我):比较高密度和低密度的组件和关系的结果。乔(P7.166)摩根富首页林明神经学神经病学FD Lippincott Williams &威尔金斯SP P7.166 VO 84 14补充A1肖恩·威尔克斯A1艾琳·麦科马克A1艾丽卡西尔弗曼A1利亚Harburg A1罗斯航道A1 Tanya Bogoslovsky A1杰森·施罗德A1卡罗尔·摩尔A1 Kimbra肯尼A1 Dzung Pham A1雷蒙Diaz-Arrastia年2015 UL //www.ez-admanager.com/content/84/14_Supplement/P7.166.abstract AB目的:定量评估进化的创伤我在第一个24小时,调查与功能的关系的结果。背景:创伤性颅内血肿的早期扩张(我)是常见的,但之前的研究集中在高密度(血液)组件。止血治疗方法旨在防止出血可能增加peri-hematoma梗塞的风险,从而增加细胞毒性水肿。评估相对进化的高和低密度组件将设计针对创伤治疗我的信息。方法:CT扫描的参与者COBRIT (Citocholine脑损伤试验)研究分析了使用MIPAV软件。CT扫描在演讲和24至48小时后被选中。包括实质我患者,而那些主要extra-axial我或我需要紧急颅骨切除术被排除在外。地区高密度和低密度测量使用阈值算法辅以目视检查。结果:配对扫描的84名患者进行了分析。 Hematoma volume increased > 50[percnt] in 34 (40[percnt]). 46 (55[percnt]) had increase in edema volume of > 50[percnt]. The correlation between expansion of the hematoma component the edema component was low (r = 0.39, p= 0.002). There was no correlation between initial or final volumes of either hematoma or edema volumes and GOSE at 3 or 6 months. There was a weak correlation between change in edema volume and GOSE at 6 months (r = 0.268, p = 0.037). There was no correlation between change in hematoma volume and GOSE at 3 or 6 months. DISCUSSION: Both high density and low density components of traumatic ICHs expand significantly in the first 2 days after TBI. There is weak or no relationship between initial volumes, final volumes, or expansion of either component and functional outcome. These results argue against use of pro-coagulant agent in traumatic ICH.Disclosure: Dr. Wilkes has nothing to disclose. Dr. McCormack has nothing to disclose. Dr. Silverman has nothing to disclose. Dr. Harburg has nothing to disclose. Dr. Passo has nothing to disclose. Dr. Bogoslovsky has nothing to disclose. Dr. Schroeder has nothing to disclose. Dr. Moore has nothing to disclose. Dr. Kenney has received royalty payments from the National Institutes of Health Technology Transfer. Dr. Pham has nothing to disclose. Dr. Diaz-Arrastia has nothing to disclose.Thursday, April 23 2015, 2:00 pm-6:30 pm