TY - T1的流行儿童共济失调的JF -神经学乔-神经病学SP - 80 LP - 89 - 10.12首页12/01. wnl.0000438224.25600.6c六世82 - 1 AU -克里斯汀e Musselman AU -克里斯蒂娜·t·Stoyanov盟Rhul Marasigan AU -玛丽·e·詹金斯盟Jurgen Konczak AU -苏珊·m·莫顿盟艾米·j·巴斯蒂安·Y1 - 2014/01/07 UR - //www.ez-admanager.com/content/82/1/80.abstract N2 -目的:评估儿童的患病率共济失调导致的遗传和后天的原因。方法:系统回顾了棱镜后(首选项报告系统评价和荟萃分析)声明。五个数据库搜索文章报道频率测量(例如,患病率,发病率)共济失调的孩子。包括文章第一次分组,根据世界卫生组织(世卫组织)地区,随后根据病因分类(遗传、收购或混合)。每一篇文章对其风险评估的偏差的域采样、测量和分析。发病率值被转换为患病率估计只要有可能。欧洲流行估计不同病因的共济失调总结评估的总体发病率童年共济失调。结果:一百一十五篇文章被包括在审查中。超过50%的数据源自欧洲地区。这个地区的数据也显示最易受偏见。小数据可供非洲和东南亚。获得性共济失调的患病率发现变化更大的跨区域比遗传性共济失调。 Ataxic cerebral palsy was found to be a significant contributor to the overall prevalence of childhood ataxia across WHO regions. The prevalence of childhood ataxias in Europe was estimated to be ∼26/100,000 children and likely reflects a minimum prevalence worldwide.Conclusions: The findings show that ataxia is a common childhood motor disorder with a higher prevalence than previously assumed. More research concerning the epidemiology, assessment, and treatment of childhood ataxia is warranted.CI=confidence interval; TAN=tropical ataxic neuropathy; WHO=World Health Organization ER -