TY -的T1的皮质表面铁尘肺患病率和机制脑淀粉样血管病JF -神经学乔-神经病学SP - 626 LP - 632 - 10.1212 / WNL。首页0 b013e3182a08f2c六世- 81 - 7盟Andreas Charidimou盟Rolf汉斯Jager AU -佐伊福克斯盟安德烈。彼得斯AU - Yves Vandermeeren盟帕特里斯Laloux盟约翰-特里男爵盟大卫回答Y1 - 2013/08/13 UR - //www.ez-admanager.com/content/81/7/626.abstract N2 -目的:我们研究了大脑皮层表面的铁尘肺的患病率和clinical-r首页adiologic协会(cSS)患者可能脑淀粉样血管病(CAA)相比脑出血(我)不属于创新艺人经纪公司。方法:我们对120例患者进行了回顾性多中心队列研究可能的创新艺人经纪公司,比较2组:67例单一大叶性我或混合(深,大叶性)出血;患者和22严格深出血。我,我们额定cSS白质变化,脑microbleeds。结果:cSS中检测出48 120 (40%;95%可信区间[CI]: 31.2% - -49.3%)患者可能的创新艺人经纪公司,67年10 (14.9%;95%置信区间:7.4% - -25.7%)与单一的大叶性我或混合出血,22日和1 (4.6%;95%置信区间:0.1% - -22.8%)患者严格深出血(p & lt;0.001趋势)。传播cSS在场120年29 (24%;95%置信区间:16.8% - -32.8%)患者可能的创新艺人经纪公司,但是我没有其他的患者(p & lt; 0.001). In probable CAA, age (odds ratio [OR]: 1.09; 95% CI: 1.03–1.15; p = 0.002), chronic lobar ICH (OR: 3.94; 95% CI: 1.54–10.08; p = 0.004), and a history of transient focal neurologic episodes (OR: 11.08; 95% CI: 3.49–35.19; p < 0.001) were independently associated with cSS. However, cSS occurred in 17 of 48 patients with probable CAA (35.4%; 95% CI: 22.2%–50.5%) without chronic lobar ICH.Conclusions: cSS (particularly if disseminated) is a common and characteristic feature of CAA. Chronic lobar ICH is an independent risk factor for cSS, but the causal direction and mechanism of association are uncertain. Hemorrhage into the subarachnoid space, independent of previous (chronic) lobar ICH, must also contribute to cSS in CAA. Transient focal neurologic episodes are the strongest clinical marker of cSS.CAA=cerebral amyloid angiopathy; CI=confidence interval; CMB=cerebral microbleed; cSAH=convexity subarachnoid hemorrhage; cSS=cortical superficial siderosis; FLAIR=fluid-attenuated inversion recovery; ICH=intracerebral hemorrhage; OR=odds ratio; T2*-GRE=T2*-weighted gradient recalled echo ER -