TY - T1的复苏的预测因子的响应能力长期缺氧植物人JF -神经学乔-神经病学SP - 464 LP - 470 - 10.1212 / WNL。首页0 b013e31827f0f31六世- 80 - 5非盟-安娜Estraneo盟Pasquale Moretta作品盟住Vincenzo洛雷托非盟- Bernardo Lanzillo盟Autilia Cozzolino AU - Annamaria Saltalamacchia盟Francesco Lullo AU -卢西奥澳网盟Luigi Trojano Y1 - 2013/01/29 UR - //www.ez-admanager.com/content/80/5/464.abstract N2 -目的:首页长期postanoxic植物人状态的病人的数量(VS)正在增加。然而,信息几乎没有对患者的长期预后标记结果仍在VS postonset超过1月。现在2年前瞻性临床研究旨在确定预后标记,记录在慢性阶段,这可能是有用的预测复苏的一群postanoxic对患者的反应。方法:我们为43住院病人长期缺氧VS(23女性;年龄12 - 83年)。我们收集的数据的病史,临床发现,在研究和神经生理学评估条目(postonset 1 - 6个月),并在24个月postonset评估与结果的关系;定义结果,患者分为响应或响应的基础上,临床标准和昏迷恢复量表——(CRS-R)。结果:9名患者恢复响应能力(但觉醒后2人死亡),而12例仍在VS和22日死于与功能性能力严重影响在所有响应幸存者。响应患者显著年轻和显示更高的CRS-R总分和登记研究的残疾评定量表评分低于患者并没有恢复。所有响应幸存者幸免瞳孔光反射和疼痛的反应,和阵发性交感神经过度活跃。 Logistic regression analysis showed that the presence of median nerve somatosensory evoked potentials and CRS-R total score ≥6 were significant predictors of recovery of responsiveness.Conclusions: Clinical features and evoked potentials are useful predictors of long-term recovery of responsiveness in patients with prolonged postanoxic VS.A-VS=anoxic vegetative state; CIRS=Cumulative Illness Rating Scale; CRS-R=Coma Recovery Scale–Revised; DRS=Disability Rating Scale; ICU=intensive care unit; MCS=minimally conscious state; NPV=negative predictive value; PPV=positive predictive value; PSH=paroxysmal sympathetic hyperactivity; VS=vegetative state; SEP=somatosensory evoked potentials ER -