TY -的T1神经学神经上皮肿瘤摩根富林明Dysembryoplastic——乔-神经病学SP - 1699 LP - 首页1707 - 10.1212 / WNL。0 b013e31826e9aa9六世- 79 - 16 AU -弗朗辛Chassoux AU -塞巴斯蒂安·罗德里戈盟查尔斯Mellerio AU -伊丽莎白Landre AU -凯瑟琳Miquel AU -巴里斯Turak AU -雅克Laschet盟让地中海AU -凉山州Roux AU -凯瑟琳Daumas-Duport AU -伯特兰Devaux Y1 - 2012/10/16 UR - //www.ez-admanager.com/content/79/16/1699.abstract N2 -目的:确定最优神经上皮肿瘤切除术在3 dysembryoplastic (DNT)组织学亚型(简单、复杂和非特异性)基首页于MRI特征。方法:在78年连续癫痫患者操作DNT, MRI特征分类如下:1型(囊性/ polycystic-like well-delineated,强烈hypointense T1), 2型(nodular-like、异构),或3型(dysplastic-like, iso / hyposignal T1,可怜的描述,灰白色物质模糊)。组织学之间的相关性,建立了神经生理研究和手术结果为每个MRI亚型。结果:1型核磁共振(25例,在时间和extratemporal地区)总是与简单或复杂的被平反种族成员。2型核磁共振(25例,主要在皮层区域)和3型核磁共振(28例,主要在内侧颞叶)与特异性的形式。病灶(EZ)根据MRI亚型不同显著(p = 0.0029)。它与1型核磁共振的肿瘤,包括perilesional皮层2型核磁共振,涉及广泛的3型核磁共振领域。皮质发育不良主要被发现在3型核磁共振(p & lt;0.0001)。 The main prognostic factors for seizure-free outcome (83%) were complete tumor (p < 0.0001) and EZ (p = 0.0115) removal. Other factors favorably influencing the outcome were a short epilepsy duration (p = 0.013) and absence of cortical–subcortical damage at the resection site (p = 0.053). Age at surgery was not related to outcome; however, cortical-subcortical damage was correlated with old age (p = 0.021). Treatment discontinuation was correlated with young age at surgery (p = 0.004) and short epilepsy duration (p = 0.001). Conclusion: We propose that resection might be restricted to the tumor in type 1 MRI and be more extensive in other MRI subtypes, especially in type 3 MRI. Early surgery and clean surgical margins are crucial for curing epilepsy. AED=antiepileptic drug; AH=amygdalo-hippocampectomy; ATL=anterior temporal lobectomy; CD=cortical dysplasia; DNT=dysembryoplastic neuroepithelial tumor; EcoG=electrocorticography; EZ=epileptogenic zone; FLAIR=fluid-attenuated inversion recovery; GWM=gray–white matter; SEEG=stereo-EEG; TLE=temporal lobe epilepsy; WM=white matter ER -