@article {Chassoux1699作者={弗朗辛Chassoux塞巴斯蒂安·罗德里戈和查尔斯Mellerio伊丽莎白Landr {\ ' e}和凯瑟琳Miquel巴里斯Turak和雅克Laschet让{\ c c} ois地中海和弗兰{\ c c} ois-Xavier Roux和凯瑟琳Daumas-Duport和伯特兰Devaux},标题= {Dysembryoplastic神经上皮肿瘤},体积={79}={16},页面= {1699 - 1707}= {2012},doi = {10.1212 / WNL。出版商0 b013e31826e9aa9} = {Wolters Kluwer健康,公司代表美国神经病学学会},文摘={目的:确定最优切除术3 dysembryoplastic神经上皮肿瘤(DN首页T)组织学亚型(简单、复杂和非特异性)基于MRI特征。方法:在78年连续癫痫患者操作DNT, MRI特征分类如下:1型(囊性/ polycystic-like well-delineated,强烈hypointense T1), 2型(nodular-like、异构),或3型(dysplastic-like, iso / hyposignal T1,可怜的描述,灰色{\ textendash}白质模糊)。组织学之间的相关性,建立了神经生理研究和手术结果为每个MRI亚型。结果:1型核磁共振(25例,在时间和extratemporal地区)总是与简单或复杂的被平反种族成员。2型核磁共振(25例,主要在皮层区域)和3型核磁共振(28例,主要在内侧颞叶)与特异性的形式。病灶(EZ)根据MRI亚型不同显著(p = 0.0029)。它与1型核磁共振的肿瘤,包括perilesional皮层2型核磁共振,涉及广泛的3型核磁共振领域。皮质发育不良主要被发现在3型核磁共振(p < 0.0001)。主要控制发作预后因素的结果(83 \ %)是完整的肿瘤(p \ < 0.0001)和除EZ (p = 0.0115)。其他因素有利影响结果是癫痫持续时间短(p = 0.013)和无皮质{\ textendash}皮层下切除部位损害(p = 0.053)。 Age at surgery was not related to outcome; however, cortical-subcortical damage was correlated with old age (p = 0.021). Treatment discontinuation was correlated with young age at surgery (p = 0.004) and short epilepsy duration (p = 0.001). Conclusion: We propose that resection might be restricted to the tumor in type 1 MRI and be more extensive in other MRI subtypes, especially in type 3 MRI. Early surgery and clean surgical margins are crucial for curing epilepsy. AED=antiepileptic drug; AH=amygdalo-hippocampectomy; ATL=anterior temporal lobectomy; CD=cortical dysplasia; DNT=dysembryoplastic neuroepithelial tumor; EcoG=electrocorticography; EZ=epileptogenic zone; FLAIR=fluid-attenuated inversion recovery; GWM=gray{\textendash}white matter; SEEG=stereo-EEG; TLE=temporal lobe epilepsy; WM=white matter}, issn = {0028-3878}, URL = {//www.ez-admanager.com/content/79/16/1699}, eprint = {//www.ez-admanager.com/content/79/16/1699.full.pdf}, journal = {Neurology} }