TY - T1的情感忽视儿童和老年脑梗死JF -神经学乔-神经病学SP - 1534 LP - 1539 - 10.1212 / WNL。首页0 b013e31826e25bd六世- 79 - 15非盟-罗伯特·s·威尔逊AU -帕特里夏·a·博伊尔盟Lei Yu -史蒂文·r·莱文盟盟-索菲亚大肠Anagnos盟阿伦·布赫曼AU -朱莉·a .施耐德盟大卫·a·贝内特Y1 - 2012/10/09 UR - //www.ez-admanager.com/content/79/15/1534.abstract N2 -目的:这项研究的目的是测试假设一个更高层次的童年逆境与脑梗塞的风险增加有关。首页纵向临床病理学研究方法:老年参与者评价儿童期不良经历(例如,情感的忽视,父母恐吓和暴力)在先前建立16-item规模。在平均3.5年的随访中,有257人死亡,与206年脑解剖(80.2)。慢性脑梗塞(总值+微观;表示为0、1或在1)确定统一的neuropathologic考试,曾在192年完成个人在这些分析。结果:童年逆境分数范围从0到31(意味着= 8.3,SD = 6.4)。在一个有序逻辑回归模型调整年龄、性别、和教育,高逆境与慢性脑梗塞的可能性。在分析儿童逆境的分量表,只有情感忽视与梗死(优势比[或]= 1.097;95%可信区间(CI) 1.048 - -1.148)。 The likelihood of infarction was 2.8 times higher (95% CI 2.0–4.1) in those reporting a moderately high level of childhood emotional neglect (score = 6, 75th percentile) vs a moderately low level of neglect (score = 1, 25th percentile). Results were comparable in subsequent analyses that controlled for lifetime socioeconomic status, cardiovascular risk factors, and an anxiety-related trait. Conclusion: Emotional neglect in childhood may be a risk factor for cerebral infarction in old age. GLOSSARYCI =confidence interval; OR =odds ratio ER -