TY -的T1 -阿尔茨海默病的风险的变化随着时间的推移,JF -神经学乔-神经病学SP - 786 LP - 791 - 10.1首页212 / WNL。0 b013e3181f0754f六世- 75 - 9盟L.E.赫伯特AU - J.L. Bienias盟台币Aggarwal盟R.S.威尔逊盟直Shah - D.A.贝内特盟盟-埃文斯D.A. Y1 - 2010/08/31 UR - //www.ez-admanager.com/content/75/9/786.abstract N2 -目的:评估的风险是否首页阿尔茨海默病(AD)的发生率随时间变化。增加人的最古老的年龄人口将增加与广告的人数。的预测增加承担的风险的大小广告是恒定的。方法:所有65岁以上的人在一个混血,地理区域定义被邀请参加一个家采访每三年。大约有10000名参与者,分层随机样本选择详细的临床评价。在每一个周期中,个体在前一个周期,决定免费广告通过考试或高分对认知功能测试,在随后的周期抽样评估事件的广告。疾病是结构化的评估和统一的时间。这些分析包括1695名受试者评估事件从1997年到2008年。结果:公元360年开发的参与者。 Change over time in risk of incident disease was assessed in logistic regression analyses including evaluation date and controlling for age, gender, education, race, interval from disease-free designation to evaluation for incident disease, and sample design. The time variable (in years) was not significant (odds ratio = 0.970, 95% confidence interval = 0.902 to 1.044). Conclusions: The null relation of evaluation date to disease incidence suggests no recent change in risk of AD over time, and supports this assumption for projections of AD. ER -