TY -的T1 -改善偏头痛在减肥手术后严重肥胖患者JF -神经学乔-神经病学SP - 1135 LP - 1138 - 10.1212 / WNL。首页0 b013e318212ab1e六世- 76 - 13盟科学博士债券AU - s Vithiananthan盟J.M.纳什非盟-托马斯j。非盟水银血压计翼Y1 - 2011/03/29 UR - //www.ez-admanager.com/content/76/13/1135.abstra首页ct N2 -目标:越来越多的研究表明,肥胖是偏头痛的加剧的因素。然而,目前还不太清楚是否减肥可能有助于缓解偏头痛在肥胖个体。我们检查是否减肥减肥手术后与改善偏头痛。方法:前瞻性研究,24偏头痛患者根据ID-Migraine过滤网进行评估之前,减肥手术后6个月。在这两个时间点,患者体重测量和报告的频率头痛的日子,平均头痛严重,headache-related残疾过去90天通过偏头痛残疾评估问卷。头痛的措施和减肥的关系的变化,这些变化是评估使用paired-sample t测试和逻辑回归,分别。结果:患者大多是女性(88%)、中年(平均年龄39.3),严重肥胖(平均身体质量指数46.6)基线。意思是(±SD)的头痛天数减少11.1±10.3术前至术后6.7±8.2 (p & lt;0.05),平均百分比后多余的体重(% EWL)的49.4%。 The odds of experiencing a ≥50% reduction in headache days was related to greater %EWL, independent of surgery type (p < 0.05). Reductions in severity were also observed (p < 0.05) and the number of patients reporting moderate to severe disability decreased from 12 (50.0%) before surgery to 3 (12.5%) after surgery (p < 0.01). Conclusions: Severely obese migraineurs experience marked alleviation of headaches after significant weight reduction via bariatric surgery. Future studies are needed to determine whether more modest, behaviorally produced weight losses can effect similar migraine improvements. Classification of evidence: This study provides Class III evidence that bariatric surgery is associated with reduction of migraine headaches in severely obese individuals. ER -