TY -的T1 -治疗卒中后抑郁和影响功能结果JF -神经学乔-神经病学SP - 1000 LP - 1005 - 10.1212 / WNL。首页0 b013e318210435e六世非盟- 76 - 11 -嗜施密德AU - k·克伦克盟H.C. Hendrie盟- t·巴卡盟J.M.萨瑟兰AU -威廉姆斯L.S. Y1 - 2011/03/15 UR - //www.ez-admanager.com/content/76/11/1000.abstract N2 -背景:卒中首页后抑郁(PSD)是常见的卒中后;然而,卒中后函数的关系是不确定的。我们的目标是1)之间的关系确定PSD在基线(1月卒中后)和功能(12周后),2)评估抑郁的影响改善12周的函数在抑郁症中基线。方法:我们完成的二次分析数据从一个队列研究的参与者和PSD。我们使用逻辑回归来确定12周的功能依赖的相关因素1)所有367名参与者和2)与PSD的174名参与者。结果:PSD队列,3特征被发现是独立与12周的依赖:增加医疗合并症(比值比(或)1.10,95%可信区间[CI] 1.02 - -1.22),增加中风的严重程度(或1.42,95%可信区间1.19 - -1.69),和增加基线抑郁严重程度(或1.13,95%可信区间1.03 - -1.23)。抑郁症严重程度显著不同的考虑之间的依赖和独立的12周(phq - 9整个队列,7.31 vs 5.18, p = 0.008;抑郁的人群,phq - 9 9.94 vs 7.27, p = 0.019)。结论:在研究参与者与PSD,抑郁症状的严重程度在基线与依赖; however, our results are inconclusive as to whether improvement of depression is independently associated with functional recovery at 12 weeks. Even if the treatment and improvement of PSD does not directly influence functional recovery poststroke, it is essential for PSD to be identified and treated due to its high symptom burden and association with other negative health and social outcomes. ER -