PT -期刊文章AU - z伊斯兰教非盟-公元前雅各布斯盟a van Belkum AU -问:d·默罕默德盟m . b .伊斯兰教非盟- p . Herbrink AU - s Diorditsa AU - s p .露比非盟- k . a . Talukder盟惠普Endtz TI -轴突的格林-巴利综合征与感染弯曲杆菌< em > < / em > - 10.1212 / WNL孟加拉国的援助。0 b013e3181cff735 DP - 2010年2月16日TA -神经首页病学第六PG - 581 - 587 - 74 IP - 7 4099 - //www.ez-admanager.com/content/74/7/581.short 4100 - //www.ez-admanager.com/content/74/7/581.full所以Neurology2010 2月16日;74 AB -背景:空肠弯曲杆菌肠炎是主要的细菌感染前格林-巴利综合征(GBS),急性传染病后免疫介导性多神经根神经病。本研究的目的是定义GBS的临床表型和孟加拉国的空肠前C感染的关系。方法:我们进行了一个潜在的匹配病例对照医院监测包括100名患者完成国家神经疾病和中风研究所的标准GBS孟加拉达卡地区从2006年到2007年。详细的临床、电生理学的、血清学和微生物学的数据得到的随访6个月。结果:GBS的影响主要是年轻的成年男性生活在农村地区。百分之六十九的患者临床前感染的证据。最常见的症状是腹泻(36%)。大多数患者有一个纯粹的运动变体GBS(92%)相对较少脑神经参与(30%)。百分之二十五的病人需要呼吸支持。 Electrophysiologic studies showed that 67% of patients had an axonal variant of GBS. Eleven patients (14%) died, and 23 (29%) remained severely disabled during the follow-up. Positive C jejuni serology was found in an unprecedented high frequency of 57% as compared with 8% in family controls and 3% in control patients with other neurologic diseases (p < 0.001). C jejuni infection was significantly associated with serum antibodies to the gangliosides GM1 and GD1a, axonal neuropathy, and greater disability. Conclusions: We report an unusually high frequency of the axonal variant of Guillain-Barré syndrome in Bangladesh, associated with preceding Campylobacter jejuni infection, severe residual disability, and high mortality. AFP=acute flaccid paralysis; AIDP=acute inflammatory demyelinating polyneuropathy; AMAN=acute motor axonal neuropathy; AMSAN=acute motor sensory axonal neuropathy; BSMMU=Bangabandhu Sheikh Mujib Medical University; DCH=Dhaka Central Hospital; DMCH=Dhaka Medical College Hospital; FC=family control; GBS=Guillain-Barré syndrome; Ig=immunoglobulin; IVIg=IV immunoglobulin; MRC=Medical Research Council; OND=other neurologic diseases.