TY - T1的径向扩散系数在偏远的视神经炎歧视视觉结果JF -神经学乔-神经病学SP - 1702 LP - 1710 - 10.1212 / WNL。首页0 b013e3181e0434d六世- 74 - 21盟R.T.奈史密斯AU - j .徐盟台币Tutlam AU - k Trinkaus盟A.H.十字盟——研究。歌Y1 - 2010/05/25 UR - http://n.neur首页ology.org/content/74/21/1702.abstract N2 -目的:扩散张量成像(DTI)量化布朗运动组织内的水。本研究的目的是为了测试是否在一个偏远的视神经炎(上),破裂的髓鞘和轴突内视神经可以通过改变DTI检测参数,以及这些改变是否与视力丧失。史的方法:七十例≥6个月前接受了DTI的视神经视觉≤(VA)的评估和对比敏感度(CS)和实验室测量的视觉诱发电位)和(光学相干断层扫描(OCT)。结果:径向扩散系数与视力(RD)相关(r =−0.61), Pelli-Robson CS (r =−0.60), 5% c (r = 0.61), 10月(r =−0.78),延迟(r = 0.61),和VEP振幅(r =−0.46)。RD分化影响的神经受影响的神经在所有视觉结果类。RD还歧视从轻度视觉障碍神经恢复正常,从深刻的视力丧失和轻度的认知障碍。RD分化健康对照组来自临床影响神经和未受影响的神经后。CS结果RD区分所有类别的5%,所有类别的Pelli-Robson CS除了正常的复苏温和的影响。结论:视神经增加径向扩散系数(RD)检测到扩散张量成像(DTI)与视觉比例下降后视神经炎。 RD can differentiate healthy control nerves from both affected and unaffected fellow nerves. RD can discriminate among categories of visual recovery within affected eyes. Optic nerve injury as assessed by DTI was corroborated by both optical coherence tomography and visual evoked potentials. 5%CS=5% contrast sensitivity; CI=confidence interval; CIS=clinically isolated syndrome; CS=contrast sensitivity; DTI=diffusion tensor imaging; FA=fractional anisotropy; MR=magnetic resonance; MS=multiple sclerosis; NMO=neuromyelitis optica; OCT=optical coherence tomography; ON=optic neuritis; PR=Pelli-Robson contrast sensitivity; RD=radial diffusivity; RNFL=retinal nerve fiber layer; ROI=region of interest; VA=visual acuity; VEP=visual evoked potential. ER -