C.L.樱桃% % 0期刊文章%一个j.s Affandi % B.J.酿造% D.J.胡克j . Creighton % s Djauzi % % D·伊姆兰% A Kamarulzaman % p . Kamerman % J.C.麦克阿瑟%一个R•摩尔% p .价格% k·史密斯%一个I.L. Tan % s Vanar % A . Wadley % S.L. Wesselingh %大肠Yunihastuti % T丙型肝炎血清阳性并不感觉神经病变的危险因素在艾滋病患者% D R 10.1212 / WNL 2010%。0 b013e3181dd436d % 首页J神经病学% P 1538 - 1542 V % 74% 19% N X背景:感觉神经病变(SN)是常见的艾滋病患者。丙型肝炎病毒(HCV)合并感染常常被作为HIV-SN风险因素,但缺乏数据支持这个。这种合作旨在检查中丙肝病毒serostatus和SN风险之间的关联流动的艾滋病毒阳性患者。横断面研究方法:艾滋病患者评估在巴尔的摩,雅加达、约翰内斯堡、吉隆坡、墨尔本和悉尼的SN(定义为支持的症状和体征)。丙肝病毒血清阳性评估作为SN使用χ2测试风险,其次是逻辑回归模型来正确的治疗风险敞口和人口统计数据。结果:共有837名患者的非洲、亚洲和白人血统进行了研究。丙肝病毒seroprevalence不同的站点(n = 104,巴尔的摩丙肝病毒+ 61%;雅加达96年51%;约翰内斯堡300年1%;吉隆坡97、10%; Melbourne 206, 16%; Sydney 34, 18%). HCV seropositivity was not associated with increased SN risk at any site, but was associated with reduced SN risk in Melbourne (p = 0.003). On multivariate analyses, the independent associations with SN were increasing age, height, and stavudine exposure. HCV seropositivity was not independently associated with an increased SN risk at any site, but associated independently with reduced SN risk in Baltimore (p = 0.04) and Melbourne (p = 0.06). Conclusions: Hepatitis C (HCV) seropositivity was not associated with increased sensory neuropathy risk among HIV-positive patients at any site. While we were unable to assess HCV RNA or liver damage, the data suggest that HCV coinfection is not a major contributor to HIV-SN. HCV = hepatitis C; SN = sensory neuropathy. %U //www.ez-admanager.com/content/neurology/74/19/1538.full.pdf

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