TY -的T1 -良好的临床结果和成功的血管再生是缺血性中风后时间JF -神经学乔-神经病学SP - 1066 LP - 1072 - 10.1212 / WNL。首页0 b013e3181b9c847六世- 73 - 13非盟- p . Khatri AU - t·阿布鲁佐AU - s d Yeatts AU - c·尼科尔斯AU - j·p·布罗德里克盟- t . a . Tomsick A2 - Y1 - 2009/09/29 UR - //www.ez-admanager.com/content/73/1首页3/1066.abstract N2 -背景:试验IV重组组织纤溶酶原激活物(rt-PA)已经证明,再乘以从症状出现缺血性中风治疗起始与逐步降低可能的临床效益,并可能没有好处超过4.5小时。IV rt-PA启动的时机与恢复血流的时机已不清楚。了解血管造影的时机再灌注和临床结果之间的关系是需要建立的时间参数经(IA)的治疗方法。方法:中风的介入管理试点试验测试结合IV / IA治疗严重缺血性中风后3小时内出现症状。隔离的影响时间血管造影再灌注的临床结果,我们只分析大脑中动脉和颈内动脉远端遮挡(2 - 3)在脑梗死溶栓再灌注成功在介入过程(& lt; 7小时)。血管造影再灌注时间被定义为时间从中风发病过程终止。良好的临床结果被定义为改良Rankin评分0 - 2在3个月。结果:54例中,只有时间血管造影再灌注和年龄独立预测血管造影再灌注后良好的临床结果。良好的临床结果的概率下降随着时间的血管造影再灌注增加(未调整p = 0.02, p = 0.01)调整和接近的情况下没有血管造影在7小时内再灌注。 Conclusions: We provide evidence that good clinical outcome following angiographically successful reperfusion is significantly time-dependent. At later times, angiographic reperfusion may be associated with a poor risk–benefit ratio in unselected patients. CI=confidence interval; IA=intraarterial; ICA=internal carotid artery; IMS=Interventional Management of Stroke; mRS=modified Rankin Score; NIHSS=NIH Stroke Scale score; rt-PA=recombinant tissue plasminogen activator; sICH=symptomatic intracranial hemorrhage; TCD=transcranial Doppler; TICI=Thrombolysis in Cerebral Infarction. ER -