RT期刊文章SR电子T1跟踪转换摩根富林明神经病学神经学乔FD Lippincott Williams &威尔金斯SP S3首页 OP S7 10.1212 / WNL。0 b013e3181974b19 VO 72是5补充1 A1理查德·b·利普顿年2009 UL //www.ez-admanager.com/content/72首页/5_Supplement_1/S3.abstract AB有时偏头痛发作频率增加。头痛专家概念化这个过程的模型设想转变成四个不同的国家:没有偏头痛,低频情景偏头痛(< 10每月头痛),高频情景偏头痛(每月10 - 14头痛),和慢性偏头痛(每月15厘米,≥头痛)。转换的方向可能会增加或减少头痛频率和受到特定风险因素的影响。总的来说,人口研究估计,章节偏头痛患者低频或高频情景偏头痛会过渡到CM以每年2.5%左右的速度。两个纵向人口研究,经常头痛的流行病学研究和正在进行的美国偏头痛患病率和预防(AMPP)研究提供纵向人口数据定义的利率和风险因素的转变。成立于2004年,随后的AMPP研究样本> 10000偏头痛患者每年4年。横断面的数据经常头痛的流行病学研究和AMPP研究显示慢性每日头痛患者有低水平的教育和家庭收入。此外,流行病学资料表明,CM患者往往是老年人和身体质量指数较高。这些研究还评估了一系列潜在风险因素与过渡到CM。 These include baseline high attack frequency, obesity, stressful life events, snoring, and overuse of certain classes of medication. In particular, opiate and barbiturate combination products contribute to migraine progression, and nonsteroidal anti-inflammatory agents are protective in patients with <10 headache days per month. The influence of medication is modified by both headache attack frequency and frequency of medication use. Although depression and anxiety are associated with an increased risk of new-onset CM, the influence of depression is accounted for by migraine disability assessment scale score, whereas the effect of anxiety may be independent of migraine disability assessment scale score. Emerging data on the longitudinal risk of CM suggest that, in a population at risk, CM may be a preventable disorder.