PT -期刊文章盟理查德·b·利普顿TI - - 10.1212 / WNL跟踪转换援助。0 b013e3181974b19 DP - 2009年2月03 TA -神经首页病学PG - S3——第六S7 - 72 IP - 5补充1 4099 - //www.ez-admanager.com/content/72/5_Supplement_1/S3.short 4100 - //www.ez-admanager.com/content/72/5_Supplement_1/S3.full所以Neurology2009 03年2月;72 AB -有时偏头痛发作频率增加。头痛专家概念化这个过程的模型设想转变成四个不同的国家:没有偏头痛,低频情景偏头痛(& lt; 10每月头痛),高频情景性偏头痛(每月10 - 14头痛),和慢性偏头痛(每月15厘米,≥头痛)。转换的方向可能会增加或减少头痛频率和受到特定风险因素的影响。总的来说,人口研究估计,章节偏头痛患者低频或高频情景偏头痛会过渡到CM以每年2.5%左右的速度。两个纵向人口研究,经常头痛的流行病学研究和正在进行的美国偏头痛患病率和预防(AMPP)研究提供纵向人口数据定义的利率和风险因素的转变。成立于2004年,随后的AMPP研究的样本在每年10000偏头痛患者为4年。横断面的数据经常头痛的流行病学研究和AMPP研究显示慢性每日头痛患者有低水平的教育和家庭收入。此外,流行病学资料表明,CM患者往往是老年人和身体质量指数较高。 These studies have also assessed a number of potential risk factors associated with the transition to CM. These include baseline high attack frequency, obesity, stressful life events, snoring, and overuse of certain classes of medication. In particular, opiate and barbiturate combination products contribute to migraine progression, and nonsteroidal anti-inflammatory agents are protective in patients with <10 headache days per month. The influence of medication is modified by both headache attack frequency and frequency of medication use. Although depression and anxiety are associated with an increased risk of new-onset CM, the influence of depression is accounted for by migraine disability assessment scale score, whereas the effect of anxiety may be independent of migraine disability assessment scale score. Emerging data on the longitudinal risk of CM suggest that, in a population at risk, CM may be a preventable disorder.