RT期刊文章SR电子T1扩散磁共振成像异常与脑病摩根富林明长期发热性癫痫发作后神经学神经学乔FD Lippincott Williams &威尔金斯SP 1304 OP 1309做wnl.0000210487.36667 10.1212/0首页1.。a5 VO 66 9 A1 j . Takanashi A1 h . Oba A1。j . Barkovich A1 h . Tada A1 y田边A1 h .我去地狱谷野生猴园A1 s藤本A1 m .加藤A1 m . Kawatani A1。Sudo A1 h .小泽A1 t Okanishi A1 m . Ishitobi A1 y Maegaki A1 y Koyasu年2006 UL http://n.neurology首页.org/content/66/9/1304.abstract AB背景:长期发作性脑病患者宣称最初症状通常在diffusion-weighted皮层下白质异常MRI(驾车)。目的:确定这些患者分享其他常见功能。方法:患者脑病预示长期癫痫发作和随后的皮层下白质异常识别MRI回顾性收集。综述了临床、实验室和放射数据。结果:17例,年龄在10个月到4年。都有长期发热性癫痫(超过1小时12例)作为他们的初始症状。随后的癫痫发作,常常成群的复杂部分发作,被认为首次发作后4到6天在16个病人。结果从正常到重度精神发育迟滞。 MRI performed within 2 days of presentation showed no abnormality. Subcortical white matter lesions were observed on DWI between 3 and 9 days in all 17 patients. T2-weighted images showed linear high intensity of subcortical U fibers in 13 patients. The lesions were predominantly frontal or frontoparietal in location with sparing of the perirolandic region. The diffusion abnormality disappeared between days 9 and 25, and cerebral atrophy was detected later than 2 weeks. Three patients having only frontal lesions had relatively good clinical outcome. Conclusions: Although the pathophysiologic mechanism remains unknown, these patients seem to have a distinctive encephalopathy syndrome. MRI is helpful in establishing the diagnosis of this encephalopathy.