PT -期刊文章盟凯瑟琳l .樱桃AU -史蒂文·l·Wesselingh盟Luxshimi Lal AU -贾斯汀·c·麦克阿瑟TI -评价艾滋病感觉神经病变的临床筛查工具援助- 10.1212/01. wnl.0000187119.33075.41 DP - 2005年12月13日TA -神经病学第六PG - 1778 - 1781 - 65 IP - 11 4099 - //www.ez-admanager.com/content/65/11/1778.short 4100 - http://n.neurolog首页y.org/content/65/11/1778.full所以Neurology2005 12月13;65 AB -目的:评估的性能特点简要临床神经病变筛查工具用于感觉神经病变复杂的艾滋病毒感染。方法:作者评估了80名患者使用简短的周围神经病变屏幕(症)。病人被定义为有神经病,如果他们都符合这个症状与体征诊断。所有的受试者都接受感官阈值测试和下肢表皮神经纤维量化使用穿孔皮肤活检为目标的措施。Results: Individuals defined as having neuropathy using the BPNS (n = 37) performed less well on sensory threshold testing than other HIV-infected individuals (p < 0.0001 for warming, cooling, and vibration) and also had lower distal calf epidermal nerve fiber densities (p < 0.0001). Individuals who had symptoms but no neuropathic signs (n = 13) did not perform differently on any objective testing compared with neuropathy-free individuals, supporting the decision to require signs as well as symptoms as an operational criterion for the diagnosis of neuropathy. Of the symptoms listed in the screening tool, the presence of numbness had the greatest diagnostic efficiency for identifying those with neuropathy. Conclusion: The Brief Neuropathy Screening Tool (and the chosen definition of neuropathy) accurately detects those HIV-infected individuals with the greatest degree of peripheral nerve dysfunction and pathology. This is a valid neuropathy screening tool for use in the context of HIV infection, and is simple enough to be applicable in resource-limited settings.