TY - T1的教育和职业前帕金森病JF -神经学乔-神经病学SP - 1575 LP - 1583——10.1212/01. wnl.000018首页4520.21744。a2六世- 65 - 10盟——r·基利奥的重点非盟- a .巴兹盟Sanft k . r . AU - b·j·彼得森AU - j·h·鲍尔盟j . e . Ahlskog盟m - b . r . Grossardt盟德安德拉德AU - d . m . Maraganore盟w·a·罗卡Y1 - 2005/11/22 UR - //www.ez-admanager.com/content/65/10/1575.abstract N2 -目的:探讨帕金森病(P首页D)与教育协会和职业使用病例对照研究设计。方法:作者使用的医疗records-linkage系统罗彻斯特流行病学项目识别所有受试者发达PD奥姆斯特德县MN,从1976年到1995年。每个事件例被年龄(±1年)和匹配性来控制人口。作者收集的信息教育和职业使用两个独立的来源的数据:一个完整的医疗记录的审查系统,接受电话采访时说。职业是使用1980标准职业分类编码。结果:主题教育9年或以上在PD的风险增加(or = 2.0;95%可信区间= 1.1 - 3.6;p = 0.02),增加教育与风险增加的趋势(线性趋势检验,p = 0.02;医疗记录数据)。 Physicians were at significantly increased risk of PD using both sources of occupational data. By contrast, four occupational groups showed a significantly decreased risk of PD using one source of data: construction and extractive workers (e.g., miners, oil well drillers), production workers (e.g., machine operators, fabricators), metal workers, and engineers. These associations with increased or decreased risk did not change noticeably after adjustment for education. Conclusion: Subjects with higher education and physicians have an increased risk of Parkinson disease (PD), while subjects with some occupations presumed to involve high physical activity have a decreased risk of PD. ER -