TY -的T1神经影像学在tia JF -神经学乔-神经病学SP - S22 LP首页 - - 10.1212 / WNL.62.8_suppl_6 S25做。S22六世- 62 - 8 5 6盟Jeffrey l .节省盟——切尔西Kidwell Y1 - 2004/04/27 UR - //www.ez-admanager.com/content/62/首页8_suppl_6/S22.abstract N2 -大脑瞬态响应动态的缺血性的侮辱。标准的脑成像技术、CT和常规MRI对动态和地区不同神经实质响应组织缺血。相比之下,这些关键组织的灌注和扩散磁共振成像允许可视化流程和提供新的见解人类脑缺血的病理生理学。此外,临床研究已经证明,传统的脑成像和扩散磁共振成像都是大量tia患者的临床使用。当前传统TIA的定义,它可以追溯到1950年代,出现神经症状是由于局灶性脑缺血在24小时内完全解决。1这个定义的缺陷,显然早在CT(大约1970年代)时代,已经被最近的核磁共振成像演示更尖锐地调查。然而,所有成像研究综述中讨论了这种传统的定义。临床tia患者经常有先前的脑缺血性事件,临床表现和沉默。常规MRI更敏感比标准CT识别这些既存的病变。在两个不同的研究中,核磁共振成像提供的证据,至少有一个的大脑梗塞在77%到81%的TIA患者。2,3⇓ Across 17 different studies, CT showed evidence of at least one infarct somewhere in the cerebrum in 0% to 68% of TIA patients. Many patients who meet conventional clinical criteria for TIA actually exhibit a new radiologic infarct on brain imaging, a phenomenon labeled by Waxman and Toole4 as “cerebral infarction with transient signs.” Conventional CT and MRI frequently demonstrate infarcts that are appropriately located to have accounted for the deficits observed during the TIA. Among patients meeting clinical criteria for TIA, 31% to 39% demonstrate neuroanatomically relevant infarcts on conventional MRI3,5⇓ and 2% to 48% … ER -