@article {D {\ ' = {} valos2187,作者。D {\ '} valos m·布兰科和美国佩德拉泽r . Leira m·卡斯特罗和j . m . Pumar y席尔瓦和j·瑟瑞娜和j·卡斯蒂略},title ={临床{\ textendash}醉酒驾车不匹配},体积={62}={12},页面= {2187 - 2192}= {2004},doi = {wnl.0000130570.41127 10.1212/01.。出版商EA} = {Wolters Kluwer健康,公司代表美国神经病学学会},文摘={目的:评估的有用性急性临床表现的严重程度之间的不匹配和diffusion-w首页eighted成像(驾车)病变在预测早期中风的结果和梗塞体积。方法:一百六十六例半球缺血性中风的{\ textquoteright} \ < 12小时持续时间进行了研究。美国国立卫生研究院卒中量表(署)评分和醉酒驾车病变的体积测量对住院和72 {\ textpm} 12小时。梗塞体积测量在t2加权或fluid-attenuated反转恢复图像在30天。早期神经功能恶化(结束)被定义为增加> = 4分两署评估。38个患者接受静脉溶栓或abciximab。临床{\ textendash}醉酒驾车不匹配(CDM)被定义为署得分> = 8和缺血性成交量驾车< = 25毫升的承认。清洁发展机制的调整影响,在72小时驾车病变扩大,梗塞在30天的增长是通过逻辑回归分析评估和广义线性模型。 Results: CDM was found in 87 patients (52.4\%). Patients with CDM had a higher risk of END than patients without CDM because NIHSS \< 8 (odds ratio [OR], 9.0; 95\% CI,1.9 to 42) or DWI lesion \> 25 mL (OR, 2.0; 95\% CI, 0.8 to 4.9). CDM was associated with an increase of 46 to 68 mL in the mean volume of DWI lesion enlargement and infarct growth in comparison with non-CDM. All the effects were even greater and significant in patients not treated with reperfusion therapies. Conclusions: Acute stroke patients with an NIHSS score of >=8 and DWI volume of <=25 mL have a higher probability of infarct growth and early neurologic deterioration. The new concept of CDM may identify patients with tissue at risk of infarction for thrombolytic or neuroprotective drugs.}, issn = {0028-3878}, URL = {//www.ez-admanager.com/content/62/12/2187}, eprint = {//www.ez-admanager.com/content/62/12/2187.full.pdf}, journal = {Neurology} }