PT -期刊文章AU - r·c·诺尔顿盟- k·d .宽松的非盟- g·克莱因盟美国Sawrie盟- g .不可或缺AU - r·a·霍金斯盟- o . s . Aassar盟k . Soohoo AU - s王盟n巴巴罗TI -体内海马葡萄糖代谢的中间的颞叶癫痫援助- 10.1212 / WNL.57.7.1184 DP - 2001 10月09 TA -神经病学第六PG - 1184 - 1190 - 57 IP - 7 4099 - //www.ez-admanager.com/content/57/7/1184.short 4100 - //www.ez-admanager.com/content/首页57/7/1184.full Neurology2001 10月09年;57 AB -背景:的出现减少了2 - [18 f] fluoro-2-deoxy-d-glucose (FDG)吸收中央的颞叶癫痫中颞区可能只是反映了灰质的损失由于海马萎缩。增加的部分由于萎缩性海马体积的影响可能会进一步增加代谢减退。方法:作者结合mri PET coregistration,灰质mri分割,部分体积校正提高海马的考试具体葡萄糖吸收壁的宠物。目标是确定1)如果相对中间的时间代谢减退是灰质的工件(海马)萎缩,2)MRI海马代谢与萎缩是否评估,和3)如果MRI部分体积校正测量海马metabolic-volume影响关系,包括癫痫偏侧性。结果:研究结果显示,同侧海马内侧颞叶癫痫(MTLE)相对觉的灰质体积的单位,而海马代谢直接与海马体积。具体地说,部分体积修正海马代谢紧密相关(r = 0.613, p & lt;0.001)和海马体积。没有部分体积校正,较弱,但仍然显著,相关(r = 0.482, p & lt;0.001)。 Degree of asymmetry was consistently greater and provided higher sensitivity of lateralization with partial volume vs non–partial volume corrected metabolic measurements. Conclusions: Although, decreased metabolism may occur in the absence of neuronal cell loss, hippocampal atrophy and presumed degree of neuronal cell loss appears to be a primary factor involved in the cause of decreased metabolism in epileptogenic hippocampi. Partial volume correction is recommended for optimal interpretation of hippocampal structure and function relationships.