作者@article {Descombes1239 ={年代。Descombes点阀盖和U.E.天然气井和c Thalamas j . Dingemanse和i .阿努尔夫议员Bareille和y Agid o . Rascol}, title = {Dual-release配方,一种新颖的原则在左旋多巴治疗帕金森疾病}{\ textquoteright}年代,体积={56}={9},页面= {1239 - 1242}= {2001},doi = {10.1212 / WNL.56.9.1239},出版商= {Wolters Kluwer健康,公司代表美国神经病学学会},文摘={一早晨剂量Dual-release配方与左旋多巴的缓释配方加benserazide一项随机、双盲、交叉研究PD患者16个波动。首页平均时间{\ textquotedblleft}在{\ textquotedblright}是短dual-release公式(43 {\ textpm} 31分钟)比与缓释配方(81 {\ textpm} 39分钟)(p \ < 0.001),而平均复发时间,{\ textquotedblleft} {\ textquotedblright}配方的相似。dual-release配方有明显短时间达到峰值浓度(达峰时间)和更大的最大浓度(Cmax)和血浆浓度时间曲线下的面积(AUC0 {\ textendash} 5 h)缓释配方,而明显的消除半衰期(t1/2)类似的配方。issn = {0028 - 3878}}, URL = {https://n.首页neurology.org/content/56/9/1239}, eprint = {//www.ez-admanager.com/content/56/9/1239.full.pdf},杂志={神经病学}}