TY - T1的颞叶癫痫手术后血清雄激素恢复正常男性JF -神经学乔-神经病学SP - 820 LP - 824 - 10.1212 / WNL.55.6.820六世- 55 - 6非盟- j·首页鲍尔AU - b Stoffel-Wagner AU - d . Flugel AU - m·克鲁格盟- j·施拉姆AU - f . Bidlingmaier盟石球Elger Y1 - 2000/09/26 UR - //www.ez-admanager.com/content/55/6/820.abstract N2 -背景:从颞叶癫痫放电可能会影响垂体轴激素的释放。如果癫痫手术影响底层的癫痫症有人可能认为血清激素浓度手术后恢复正常。病人:22 25 - 48岁男性癫痫(意思是,34.9年)手术前进行调查,3、6和12个月后手术。药物治疗(所有患者接受卡马西平)是手术后维护。方法:激素测量包括促黄体激素,促卵泡激素、雌二醇、睾酮、游离睾酮、雄烯二酮、催乳素、硫酸脱氢表雄酮、皮质醇、生长激素和性hormone-binding球蛋白。这些激素水平与105年相比健康男性(平均年龄33.9岁)。结果:十四22名患者(63.6%)达到了总发作控制癫痫手术后。14成功控制癫痫患者进入进一步分析。手术前病人的游离睾酮和雄烯二酮浓度与健康男性相比显著降低。的14名患者显著增加激素血清睾酮浓度可以证明,游离睾酮和雄烯二酮。 Laterality of epileptic focus, enzyme-inducing medication, stress, and the decreasing number of patients during the follow-up did not correlate with the finding of a normalization of serum androgens. Patients without complete seizure control did not show an increase in serum androgen concentrations. Conclusion: Successful temporal lobe epilepsy surgery may lead to a normalization of serum androgen concentrations in men with epilepsy. ER -