RT期刊文章SR电子T1不利长期影响成人轻度神经胶质瘤患者脑放疗的摩根富林明神经病学神经学乔FD Lippincott Williams &威尔金斯SP 1285 OP 1290 10.1212 / WNL.56.10.1285 VO 56是1首页0 A1 o . Surma-aho A1 m . Niemela A1 j . Vilkki A1 m . Kouri A1。打烙印A1 o . Salonen A1。Paetau A1 m . A1与j . Pyykkonen LicPhil A1 j·科年2001 UL //www.ez-admanager.com/content首页/56/10/1285.abstract AB目的:研究长期放射治疗对认知功能的影响在成人为低级神经胶质瘤病人动手术。方法:160年一群病人手术低级神经胶质瘤的大脑半球在1980年和1992年之间在一个单一的机构服务定义的人口进行了研究。的平均随访时间7年,28岁的101患者术后辐照(和没有第二个手术或化疗)还活着和合格的MRI和神经心理学研究。23 59岁的患者没有放射治疗,第二次手术或化疗还活着和合格的意思是10年。结果:术后的组辐照表现明显比那组没有在认知测试。这种差异不是由组织学诊断;位置、程度切除或肿瘤的进展;或任何病人的因素。 Leukoencephalopathy was more severe in the group that had postoperative irradiation than in the group without radiotherapy, and correlated to poor memory performances only in the postoperative radiotherapy group. Average Karnofsky performance scale score was significantly lower in the group that had postoperative irradiation than in the group that did not. Conclusion: In adults with low-grade glioma, postoperative radiotherapy poses a significant risk of long-term leukoencephalopathy and cognitive impairment.