% 0期刊文章%一个约瑟夫·卡斯罗西尼Samudralwar % %史蒂文风箱%科里戈德史密斯% T表示,诊断困难,治疗措施情况下的孤立coccodioidomycosis脑膜炎免疫活性的个人(P3.310) % D J神经病学2017% % P P3.310 X % V % 88% N 16补充目的:我们报告一例球孢子菌病的免疫活性的个人没有以前的历史呈现与中枢神经系统的参与球孢子菌病脑膜炎,脑积水,没有其他系统性疾病的形式。首页背景:球孢子菌病是一种真菌疾病,通常主要表现为肺部感染。60%无症状但表现症状往往处于免疫功能不全的状态,很多时候有一个致命的结果。肺外球孢子菌病更为罕见,通常体现在最初肺参与。不太常见的是初始与中枢神经系统(CNS)表示一种免疫活性的个人和之前没有任何已知的疾病。一个可行的患者免疫系统通常无症状或轻度病毒性疾病,自行消退。设计/方法:这是一个案例报告鉴别诊断困难,治疗为病人确定为免疫活性的临床暴发性的迹象,但面对孤立coccodioidomycosis脑膜炎。免疫活性的结果:39岁男性患有慢性头痛,成为与视觉相关的赤字,失衡,并最终脑病,发现脑积水。软脑膜显影并且初始CSF研究模糊时从心室排水,但是重复腰椎水箱的研究显示传染病的存在。广泛的污迹coccodioidomycosis透露他是积极的,要求氟康唑与症状的改善。MRI显示增强降低脑积水底水箱以及改善。严重程度的表示和hydrocephalous上成像,这是符合需要继续氟康唑终身。Conclusions: This case outlines the severity of presentation of fungal disease that can present even with immunocompetence, the pitfalls in CSF studies when obtained from different areas of the ventricular system, and the determination of therapeutics. Given severity of presentation and likely with the aid of an intact immune system, the patient had a remarkable clinical recovery.Disclosure: Dr. Samudralwar has nothing to disclose. Dr. Kass has received personal compensation for activities as an expert witness in litigation. Dr. Kass has received personal compensation as a speaker at non-commercial CME talks for primary care physicians. Dr. Kass has received personal compensation in an editorial capacity for the Ethics and Medicolegal Issues for Continuum: Lifelong Learning in Neurology and Continuum Audio. Dr. Bellows has nothing to disclose. Dr. Goldsmith has nothing to disclose. %U

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