TY - T1的测试腔隙的有效性假设JF -神经学乔-神经病学SP - 1204 LP - 1211 - 10.1212 / WNL.首页48.5.1204六世- 48 - 5 AU - r . Gan盟r . l . AU - d . e . Kargman盟的焦点在于j·k·罗伯茨AU - b . Boden-Albala AU -问:顾Y1 - 1997/05/01 UR - //www.ez-admanager.com/content/48/5/1204.abstract N2 Backgrouncd /目标很少有研究试图验证“腔隙假说。“确定腔隙的准确性和其他nonlacunar梗死机制将在评估潜在的中风治疗方法变得越来越重要。本研究的目的是确定腔隙综合征的价值的值预测放射陷窝和clinicoradiologic陷窝在预测“腔隙梗塞”最终中风的机制。方法从1990年到1994年,591例脑梗死患者,他们从曼哈顿北部和39岁的前瞻性研究。数据收集承认临床综合征(腔隙或nonlacunar)和脑成像结果。腔隙综合征被归类为纯电机轻偏瘫(PMH),纯感官综合征(PSS)、感觉运动综合症(SMS), ataxic-hemiparesis (a),和其他腔隙综合征。脑成像研究结果分为辐射缝隙或nonlacune。阳性预测值、敏感性和特异性识别的腔隙综合征放射陷窝。梗死的最终机制确定后的腔隙之间的诊断测试和比较组。结果腔隙综合征发生在225例。PMH是最常见的腔隙综合征,占45%,短信20%,a - 18%, PSS 7%。 Lacunar syndromes had an overall positive predictive value (PPV) of 87% for detecting radiologic lacune: PSS loo%, A-H 95%, SMS 87%, and PMH 79%. Among the 195 patients who presented with a lacunar syndrome and had this condition confirmed radiologically, 147 were classified as having a final diagnosis of lacunar mechanism of infarction (PPV = 75%). Atherosclerosis accounted for 17 (9%), cardioembolism 10 (5%), cryptogenic 17 (9%), and other unusual causes 4 (2%). Conclusion While lacunar syndromes, especially PSS and A-H, are highly predictive of lacune, in about one in four patients presenting with lacunar syndromes confirmed radiologically the condition is associated with nonlacunar mechanisms of infarction. Noninvasive neurovascular and cardiac evaluations are still warranted even among patients with lacunes. ER -