TY - T1的时空中风负担趋势归因于环境PM 2.5 <子> < /订阅>在204个国家和地区,1990 - 2019年摩根富林明-神经学乔-神经病学SP - e764 LP - - 10.1212 / WNL e776做。首页0000000000207503六世- 101 - 7盟Yacong博盟Yongjian朱盟Xiaoan张盟-回族张盟Junxi张盟-香钱老挝盟Zengli Yu Y1 - 2023/08/15 UR - //www.ez-admanager.com/content/101/7/e764.abstract N2 -背景和目标之前的研究表明,长期暴露在周围的细颗首页粒物(PM2.5)与中风的风险增加相关。然而,有限的研究评估中风负担归因于环境PM2.5在全球范围内,特别是组成在不同的地区,国家,社会经济水平。因此我们进行这项研究估计周围的空间和时间趋势PM2.5-related中风负担按性别、年龄、和亚型从1990年到2019年在全球、地区和国家的水平。方法信息环境PM2.5-related中风负担从1990年到2019年从2019年全球疾病负担研究获得。中风的负担归因于环境PM2.5(即。年龄标准化死亡率(纳)和年龄标准化率(正如))的残疾调整生命年估计按性别、年龄、和亚型从1990年到2019年在全球、地区和国家的水平。估计年度百分比变化(EAPC)是用来评估正如的变化趋势和纳归因于环境PM2.5从1990年到2019年。斯皮尔曼相关系数是用于检查社会人口之间的关系指数(SDI)和EAPC纳德,正如在国家层面。结果在2019年,全球环境PM2.5-related中风死亡率和残疾调整生命年114万年和2874万年,分别与相应的正如纳每100000人口,348.1和14.3。正如和纳随着年龄的增加,最高的男性患者,在中间SDI地区,对于脑出血(我)。 From 1990 to 2019, the absolute death number of stroke attributable to ambient PM2.5 and the corresponding ASMR and ASDR were both in an increasing trend. The corresponding EAPCs in ASMR and ASDR were 0.09 (95% CI −0.05 to 0.24) and 0.31 (95% CI 0.18–0.44), respectively. The significant increases of ASMR and ASDR were observed in the low, low-middle, and middle SDI regions, and for ICH. However, a decreasing trend was observed in high and middle-high SDI regions, and for subarachnoid hemorrhage.Discussion The global burden of stroke attributable to ambient PM2.5 showed an increasing trend over the past 30 years, especially in male patients, low-income countries, and for ICH. Continued efforts on reducing the level of ambient PM2.5 are necessary to reduce the burden of stroke.ASDR=age-standardized disability-adjusted life-year rate; ASMR=age-standardized mortality rate; ASR=age-standardized rate; DALY=disability-adjusted life year; EAPC=estimated annual percentage change; GBD=Global Burden of Disease; ICH=intracerebral hemorrhage; IS=ischemic stroke; PM2.5=particulate matter; SAH=subarachnoid hemorrhage; SDI=sociodemographic index; UI=uncertainty interval; WHO=World Health Organization; YLD=year lived with disability; YLL=year of life lost ER -