TY -的T1 -全球障碍的诊断多发性硬化症JF -神经学乔-神经病学SP - e624 LP - e635做- 10.1212 / WNL。首页0000000000207481六世- 101 - 6非盟-安德鲁·j·所罗门AU -露丝安Jorge Correale上非盟-尚Viswanathan盟盟-梅林达Magyari盟-尼尔·p·罗伯逊盟迪安娜·r·塞勒AU -温迪凯盟林赛Rechtman AU - Eunchan Bae盟盟罗素Shinohara -雷切尔王盟乔安娜Laurson-Doube AU -安妮·赫尔姆Y1 - 2023/08/08 UR - //www.ez-admanager.com/content/101/6/e624.abstract N2 -背景和目标最近的数据表明增加全球流行的多发性硬化症(MS)。首页早期诊断的MS减少残疾调整生命年的负担和相关医疗费用。然而诊断延误坚持照顾女士,即使在国家卫生保健系统和强大的资源,全面登记,女士subspecialist转诊网络。全球患病率和加速女士障碍诊断的特点,尤其是在resource-restricted地区,并没有被广泛地研究过了。最近修正MS诊断标准展示潜力促进早期诊断,但全球实现在很大程度上仍是个未知数。方法多发性硬化症国际联合会第三版的阿特拉斯女士是一个调查,评估当前的全局状态的诊断包括采用MS诊断标准;障碍诊断的病人,卫生保健提供者,和卫生系统;和存在的国家指导方针或国家标准速度的诊断。结果来自107个国家的协调员(约占世界人口的82%),参与。 Eighty-three percent reported at least 1 “major barrier” to early MS diagnosis. The most frequently reported barriers included the following: “lack of awareness of MS symptoms among general public” (68%), “lack of awareness of MS symptoms among health care professionals” (59%), and “lack of availability of health care professionals with knowledge to diagnose MS” (44%). One-third reported lack of “specialist medical equipment or diagnostic tests.” Thirty-four percent reported the use of only 2017 McDonald criteria (McD-C) for diagnosis, and 79% reported 2017 McD-C as the “most commonly used criteria.” Sixty-six percent reported at least 1 barrier to the adoption of 2017 McD-C, including “neurologists lack awareness or training” by 45%. There was no significant association between national guidelines pertaining to MS diagnosis or practice standards addressing the speed of diagnosis and presence of barriers to early MS diagnosis and implementation of 2017 McD-C.Discussion This study finds pervasive consistent global barriers to early diagnosis of MS. While these barriers reflected a lack of resources in many countries, data also suggest that interventions designed to develop and implement accessible education and training can provide cost-effective opportunities to improve access to early MS diagnosis.GOF=Goodness of Fit; McD-C=McDonald criteria; MS=multiple sclerosis; MSIF=Multiple Sclerosis International Federation; OR=odds ratio; WB=World Bank; WHO=World Health Organization ER -