RT期刊文章SR电子T1常见的神经系统疾病负担在亚洲国家,1990 - 2019年:2019年全球疾病负担研究分析摩根富林明神经病学神经学乔FD Lippincott Williams &威尔金斯10.1212 SP / WNL。首页0000000000207218 10.1212 / WNL。0000000000207218 A1悦王A1晶晶梁A1个方A1 Dongxiao姚明A1莉莉周张A1实证A1 Yajuan王陆A1鲁玉胡锦涛A1 Zuneng A1仪陇王A1 Zheman肖年2023 UL //www.ez-admanager.com/content/early/2023/04/03/WNL.0000000000207218.abstract AB背景和objectiv首页esBased全球疾病负担,伤害,和风险因素(GBD)的研究中,神经系统疾病是全球发病率和死亡率的主要原因。然而,没有全面的评估在亚洲神经障碍。GBD 1990 - 2019年的数据研究了在亚洲为神经系统疾病提供新的细节。MethodsThe常见神经系统疾病负担1990年和2019年在亚洲计算发病率,患病率,死亡和伤残调整寿命(残疾)。分析了13个常见的神经系统疾病。数据提出了总量和按性别、年龄、位置、危险因素和socio-demographic指数(SDI)和显示为数量和利率。ResultsIn 2019年亚洲最繁重的神经障碍对残疾是中风的绝对数量(9880万[95% UI, 91.0∼107.0]),偏头痛(2460万[95% UI, 3.4∼56.4]),阿尔茨海默病(AD)和其它痴呆(1350万[95% UI, 5.9∼29.8])。从1990年到2019年,残疾和死亡的绝对数量合并神经系统疾病引起的(死亡和60.7%的残疾17.6%)增加,但年龄标准化的利率(死亡和34.1%的残疾36.3%)下降。神经系统疾病的负担个人65 - 74岁之间达到顶峰,男性高于女性; moreover, this burden varied considerably across Asian subregions and countries. Risk-attributable DALYs accounted for 86.9%, 28.5%, and 11.1% of DALYs for stroke, AD and other dementias and multiple sclerosis (MS), respectively. For communicable neurological disorders, the crude rates of all metrics were moderately to strongly negatively correlated with the SDI, while the crude rate of stroke prevalence was moderately positively correlated with the SDI.ConclusionNeurological disorders were the leading cause of DALYs and the second leading cause of deaths in Asia in 2019, and the burden may likely increase with the growth and aging of the Asian population. Urgent measures are needed for prevention, treatment, rehabilitation, and support services for common neurological disorders regionally and nationally.