PT -期刊文章AU -悦王盟-梁晶晶盟方个AU - Dongxiao姚明盟莉莉张盟-实证周盟Yajuan王盟鲁玉胡AU -陆Zuneng盟仪陇王盟Zheman肖TI -常见的神经系统疾病负担在亚洲国家,1990 - 2019年:2019年全球疾病负担研究分析- 10.1212 / WNL援助。0000000000207218 DP - 2023年4月04 TA -神经病首页学PG - 10.1212 / WNL。0000000000207218 4099 - http://n.首页neurology.org/content/early/2023/04/03/WNL.0000000000207218.short 4100 - //www.ez-admanager.com/content/early/2023/04/03/WNL.0000000000207218.full AB -背景和objectivesBased全球疾病负担,伤害,和风险因素(GBD)的研究中,神经系统疾病是全球发病率和死亡率的主要原因。然而,没有全面的评估在亚洲神经障碍。GBD 1990 - 2019年的数据研究了在亚洲为神经系统疾病提供新的细节。MethodsThe常见神经系统疾病负担1990年和2019年在亚洲计算发病率,患病率,死亡和伤残调整寿命(残疾)。分析了13个常见的神经系统疾病。数据提出了总量和按性别、年龄、位置、危险因素和socio-demographic指数(SDI)和显示为数量和利率。ResultsIn 2019年亚洲最繁重的神经障碍对残疾是中风的绝对数量(9880万[95% UI, 91.0∼107.0]),偏头痛(2460万[95% UI, 3.4∼56.4]),阿尔茨海默病(AD)和其它痴呆(1350万[95% UI, 5.9∼29.8])。从1990年到2019年,残疾和死亡的绝对数量合并神经系统疾病引起的(死亡和60.7%的残疾17.6%)增加,但年龄标准化的利率(死亡和34.1%的残疾36.3%)下降。神经系统疾病的负担个人65 - 74岁之间达到顶峰,男性高于女性; moreover, this burden varied considerably across Asian subregions and countries. Risk-attributable DALYs accounted for 86.9%, 28.5%, and 11.1% of DALYs for stroke, AD and other dementias and multiple sclerosis (MS), respectively. For communicable neurological disorders, the crude rates of all metrics were moderately to strongly negatively correlated with the SDI, while the crude rate of stroke prevalence was moderately positively correlated with the SDI.ConclusionNeurological disorders were the leading cause of DALYs and the second leading cause of deaths in Asia in 2019, and the burden may likely increase with the growth and aging of the Asian population. Urgent measures are needed for prevention, treatment, rehabilitation, and support services for common neurological disorders regionally and nationally.