新诊断局灶性癫痫患者的情绪、焦虑障碍与自杀行为[j] [j] [j] [j] [j] [j] [j] [j] [j] [j] [j]首页签证官100年11 A1安德烈斯·m·Kanner A1 Anita s Saporta A1董h . Kim A1约翰·j·巴里A1岩漠Altalib A1希望Omotola A1娜塔莉Jette A1特伦斯j . O ' brien A1悉达多纳卡尼A1旋律r . Winawer A1迈克尔·斯珀林A1杰奎琳·a .法国A1巴塞尔因车祸Abou-Khalil A1布莱恩Alldredge A1玛蒂娜Bebin A1格雷戈里·d·Cascino A1安德鲁·j·科尔A1马克·j·库克A1卡米尔Detyniecki A1奥林Devinsky A1丹尼斯Dlugos A1爱德华Faught A1大卫·菲克A1 A1巴里Gidal A1迈克尔·玛德琳字段Gelfand A1西蒙·格林A1乔纳森·j·哈尔福德A1谢丽尔上流社会的A1马努对冲基金A1 Manisha g .福尔摩斯A1 Reetta Kalviainen A1俊康A1帕维尔•克莱恩A1罗伯特·c·诺尔顿A1 Kaarkuzhali•A1鲁本Kuzniecky A1帕特里克关颖珊A1丹尼尔·h·洛温斯坦A1劳拉马尔库塞A1 Kimford j . tommeador一路A1斯科特·明茨A1希思r . Pardoe A1克里斯汀公园A1 Patricia Penovich A1王妃K·辛格A1欧内斯特·萨默维尔A1查尔斯·a·萨博A1 Jerzy p Szaflarski A1 K。Liu Lin Thio A1 Eugen Trinka A1 Jorge G. Burneo A1和人类癫痫项目YR 2023 UL //www.ez-admanager.com/content/100首页/11/e1123.abstract AB背景和目的情绪、焦虑障碍和自杀在癫痫患者中比在一般人群中更常见。然而，在癫痫诊断时与自杀相关的情绪和焦虑障碍的患病率和类型尚未确定。我们试图在新诊断的局灶性癫痫患者中回答这些问题，并评估其与自杀意念和企图的关系。方法数据来源于人类癫痫项目研究。在开始治疗的4个月内，共有347名18-60岁新诊断为局灶性癫痫的连续成年人入组。心境和焦虑障碍的类型通过迷你国际神经精神病学访谈确定，而自杀意念(终生、当前、主动和被动)和自杀企图(终生和当前)则通过哥伦比亚自杀严重程度评定量表(CSSRS)确定。统计分析包括t检验、χ2统计和logistic回归分析。结果151例(43.5%)患者有精神科诊断;134人(38.6%)符合情绪和/或焦虑障碍的标准，75人(21.6%)报告有或没有自杀企图。 Mood (23.6%) and anxiety (27.4%) disorders had comparable prevalence rates, whereas both disorders occurred together in 43 patients (12.4%). Major depressive disorders (MDDs) had a slightly higher prevalence than bipolar disorders (BPDs) (9.5% vs 6.9%, respectively). Explanatory variables of suicidality included MDD, BPD, panic disorders, and agoraphobia, with BPD and panic disorders being the strongest variables, particularly for active suicidal ideation and suicidal attempts.Discussion In patients with newly diagnosed focal epilepsy, the prevalence of mood, anxiety disorders, and suicidality is higher than in the general population and comparable to those of patients with established epilepsy. Their recognition at the time of the initial epilepsy evaluation is of the essence.ASM=antiseizure medication; BPD=bipolar disorder; CSSRS=Columbia Suicidality Severity Rating Scale; MDD=major depressive disorder; MDE=major depressive episode; MINI=the Mini International Neuropsychiatric Interview; SA=suicidal attempt; SI=suicidal ideation; PWE=people with epilepsy