TY - JOUR T1 -气候变化和空气污染对神经健康、疾病和实践的影响JF -神经学JO -神经学SP - 474 LP - 483 DO - 10.1212/WNL.0000000000201630首页六世- 100 - 10盟路易Shreya AU -卡尔森,Alise k . AU -苏雷什,身为理发师AU - Rim,约书亚AU -梅斯,玛丽安非盟- Ontaneda,丹尼尔•Dhawan盟——安德鲁Y1 - 2023/03/07 UR - //www.ez-admanager.com/content/100/10/474.abstract N2 -背景和目标尽管国际首页社会共同寻求降低全球温度上升小于1.5°C在2100年之前,不可逆转的环境变化已经发生,并且随着全球变暖,这些变化将继续发生。当我们目睹地球变暖对人类健康的影响时，神经学家必须预测神经疾病的流行病学和发病率可能发生的变化。在这篇综述中，我们围绕与气候变化和神经健康相关的3个关键主题组织了我们的分析:极端天气事件和温度波动、新出现的神经传染病和污染物影响。在这些主题中，我们评估并回顾了最近与神经疾病和实践相关的文献。方法使用PubMed、OVID MEDLINE、EMBASE、PsycInfo和灰色文献中与气候变化、污染物和神经疾病相关的搜索词来确定研究。如果1990年至2022年期间发表的研究与人类发病率或患病率有关，并且是英文的，并且与神经系统疾病有关，那么这些研究将被纳入。结果我们共确定了364篇文章，归类为我们研究的3个关键主题:极端天气事件和温度波动(38项研究)，新兴神经感染性疾病(37项研究)和污染物影响(289项研究)。纳入的研究强调了神经症状恶化与温度变异、蜱传感染与气候变暖、空气污染物与脑血管疾病发病率和严重程度之间的关系。极端温度和温度变异性都与中风发病率和严重程度、偏头痛、痴呆患者住院和多发性硬化症加重有关。 Exposure to airborne pollutants, especially PM2.5 and nitrates, associated with stroke incidence and severity, headaches, dementia risk, Parkinson disease, and MS exacerbation. Climate change has demonstrably expanded favorable conditions for zoonotic diseases beyond traditional borders and poses the risk of disease in new, susceptible populations. Articles were biased toward resource-rich regions, suggesting a discordance between where research occurs and where changes are most acute. As such, 3 key priorities emerged for further study: neuroinfectious disease risk mitigation, understanding the pathophysiology of airborne pollutants on the nervous system, and methods to improve delivery of neurologic care in the face of climate-related disruptions.ALS=amyotrophic lateral sclerosis; ED=emergency department; ICH=intracerebral hemorrhage; JEV=Japanese encephalitis virus; MS=multiple sclerosis; PD=Parkinson disease; TBE=tick-borne encephalitis; WHO=World Health Organization ER -