@article {GabarinS50作者= {Ramy Gabarin和朱利安H {\ ' e}伯特Seth Climans和亚历山德拉Muccilli悉尼和理查德·李和格雷戈里天Wennberg大卫Tang-Wai}, title ={自身免疫性脑炎的长期精神病症状缓解},体积={99},数量={23补充2},页面= {S50——S50} = {2022}, doi = {10.1212/01. wnl.0000903408.52359.84},出版商= {Wolters Kluwer健康,公司代表美国神经病学学会},文摘={目的确定自我抑郁和焦虑症状的患病率在缓解患者自身免疫性脑炎(AE)。首页背景虽然之前研究发现高患病率的残余认知障碍患者在缓解AE,有一个缺乏这类患者长期精神结果数据。在正常人群,中位数病人健康Questionaire-9 (PHQ9)和一般焦虑Disorder-7 (GAD7)分数据报道,分别为3和2左右,与抑郁和焦虑症状的患病率在这些问卷调查报告为24 \ %和23 \ %。设计/方法回顾性横断面队列研究在三级中心AE诊所在2012-01-01和2012-01-01之间。患者通过电话联系或定期随访和PHQ9和GAD7完成。结果41例患者联系;29日(71 \ %),包括回应。17(59 \ %)是女性。平均年龄为32.5岁(范围5 - 77)。n -甲基- d受体自身抗体结果(48 n = 14日\ %)、负(n = 7, 24 \ %),富亮氨酸glioma-inactivated 1 (n = 6, 21 \ %),和contactin-associated蛋白质像2 (n = 1, 3 \ %)。从发病到问卷收集的平均时间为6.3年(范围1.5 - -23.0)。10例(37 \ %)正在经历抑郁的症状以PHQ9, 6(60 \ %)报告严重的症状。PHQ9得分中位数为3(范围0-18)。 Six patients (22\%) were experiencing symptoms of anxiety on the GAD7, with one (17\%) reporting moderate-to-severe symptoms. Median GAD7 score was 2 (range 0-10). Eight patients (28\%) reported a psychiatric history prior to the onset of AE, which was associated with increased PHQ9 scores (p = 0.04, Wilcoxon rank sum test).Conclusions The prevalence of self-reported depressive and anxious symptoms in this cohort in remission from AE was similar to general populations. Patients with a psychiatric history that preceded onset of AE had higher PHQ9 scores. These results may be affected by censoring bias and lower sensitivity of self-reported diagnostic tools.}, issn = {0028-3878}, URL = {//www.ez-admanager.com/content/99/23_Supplement_2/S50.1}, eprint = {//www.ez-admanager.com/content/99/23_Supplement_2/S50.1.full.pdf}, journal = {Neurology} }