PT -期刊文章盟-尼古拉Jaime Adderley盟Anuradhaa萨勃拉曼尼亚AU -玛丽铂金斯盟Krishnarajah Nirantharakumar AU -苏珊·p·Mollan盟亚历山德拉吉恩·辛克莱TI -头痛、麻醉剂使用,女性特发性颅内高血压处方趋势- 10.1212 / WNL援助。0000000000201064 DP - 2022年11月01 TA -神经首页病学PG - e1968 e1978 VI - 99 IP - 18 4099 - //www.ez-admanager.com/content/99/18/e1968.short 4100 - //www.ez-admanager.com/content/99/18/e1968.full所以Neurology2022 11月01;99 AB -背景和目标医生处方习惯鸦片和头痛疗法之前尚未评估在一个大的,匹配的队列研究特发性颅内高血压(IIH)。我们的目标是评估鸦片和头痛药物处方习惯与匹配的女性相比,颅内高压症女性偏头痛和人口控制。我们也调查了新发作的头痛的发生颅内高压症与人口控制。我们进行以人群为基础的匹配方法,回顾性队列研究来探索头痛的结果。横断面分析用来描述药物处方模式。我们使用数据从IQVIA医学研究数据,一个匿名,全国代表性初级护理电子病历数据库在英国,从1995年1月1日至2019年9月25日。16岁以上的女性都有资格列入。女性颅内高压症(暴露),年龄和身体质量指数与10控制女性没有颅内高压症但偏头痛(偏头痛控制),和没有颅内高压症或偏头痛(人口控制)。结果共有3411名妇女与颅内高压症13966偏头痛控制,和33495人口控制是包括在内。新出现的调整风险比头痛在颅内高压症与人口控制为3.09 (95% CI 2.78 - -3.43)。 In the first year after diagnosis, 58% of women with IIH were prescribed acetazolamide and 20% topiramate. In total, 20% of women with IIH were prescribed opiates within the first year of their diagnosis, reducing to 17% after 6 years, compared with 8% and 11% among those with migraine, respectively. Twice as many women with IIH were prescribed opiates compared with migraine controls, and 3 times as many women with IIH were prescribed opiates compared with population controls. Women with IIH were also prescribed more headache preventative medications compared with migraine controls.Discussion Women with IIH were more likely to be prescribed opiate and simple analgesics compared with both migraine and population controls. Women with IIH trialed more preventative medications over their disease course suggesting that headaches in IIH may be more refractory to treatment.BMI=body mass index; CGRP=calcitonin gene-related peptide; IIH=idiopathic intracranial hypertension; IMRD=IQVIA Medical Research Data; THIN=The Health Improvement Network