RT杂志文章SR电子T1首页(S8.005) JF Neurology JO Neurology FD Lippincott Williams & Wilkins SP S8.005 VO 88 IS 16 Supplement A1 Maxim Mulder A1 Saliha Ergezen A1 Hester Lingsma A1 Olvert Berkhemer A1 Puck Fransen A1 Debbie Beumer A1 Lucie Van den Berg A1 Geert Lycklama a Nijeholt A1 Bart Emmer A1 Bart Van der Worp A1 Paul Nederkoorn A1 Yvo Roos A1 Robert Van Oostenbrugge A1 Wim Van Zwam A1 Charles Majoie A1 Aad Van der Lugt A1 Diederik Dippel YR 2017 UL //www.ez-admanager.com/content/88/16_Supplement/S8.005.abstract AB Objective: We aimed to assess the relation between blood pressure (BP) and functional outcome and intra-arterial treatment (IAT) effect, occurrence of symptomatic intracranial hemorrhage (SICH).Background: High BP is associated with poor outcome in acute ischemic stroke, but whether BP influences the benefit or safety of IAT is not known.Design/Methods: This is a post-hoc analysis of the Multicenter Randomized Clinical Trial of Endovascular Treatment of Acute Ischemic Stroke in the Netherlands (MR CLEAN).BP测量基准点,随机化后,IAT前估计基线BP和修改Rangin尺度得分关联90天安全参数与序式回归分析BP对IAT效益的多重交互条件测试 Results:sistlic BP(SBP)与功能结果最相关关联性为U形低高基线SBP都与不良功能结果相关联。高SBP与SICH相关联(调整概率比=1.25SBP中每10毫米加汞[95%CI:1.09-1.44])。SBP和IAT之间没有函数结果交互性,SICH或其它安全参数IAT绝对利益在整个SBP范围显而易见诊断性BP发现相同情况。 结论:血压不影响IAT对因近似内部隔离引起急性缺血性中风的病人的益或安全MRCLEAN测试部分由荷兰心脏基金会和AngioCareBV、Medtronic/Covidien/EV3Q、MEDACGmbh/LAMEPRO、Penumbra公司、StrykerQQ和Top医学/Concent穆德没有什么可透露博士ERGEZEN没有什么可透露博士sma没什么可透露博士Berkhemer没有什么可透露博士弗朗森无关披露博士Beumer没有什么可透露博士VandenBerg没什么可透露博士LycklamaNije博士Emmer没什么可透露博士Van Der Worp从荷兰心脏基金会、AngioCareBV、Medtronic/Coviden/EV3博士Nederkoorn没有什么可透露博士Roos没什么可透露博士VanOostenbruge没有什么披露博士VanZwam机构因Stryker和Codman担任顾问而获得补偿博士Majoie机构因担任Stryker顾问而获得补偿博士Vander Lugt没有什么可透露博士Dippel因Stryker咨询公司的活动而获得个人补偿

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