@article {Martinez-Hernandez4170作者= {Eugenia马丁斯和戴安娜Esteller玛丽亚赛普维达和莎拉Llufriu Mar Guasp何塞玛丽亚卡布瑞拉和阿尔瓦罗·卡巴约蒙特塞拉特Artola安娜Hernando和弗朗西斯克格劳尤兰达布兰科Morgado和艾伯特Saiz}, title = {COVID-19发生率和影响的一群从巴塞罗那重症肌无力患者。(4170)},体积={96}={15}补充数量,elocation-id ={4170} ={2021},出版商= {Wolters Kluwer健康,公司代表美国神经病学学会},文摘={目的:描述发病率、临床特征和影响COVID-19在一群成年患者重症肌无力(MG)。首页背景:目前还不清楚如果MG患者的风险增加发展中COVID-19,如果大流行增加了MG发作。设计/方法:横断面研究评估通过电子邮件/电话采访75 MG病人在医院诊所,巴塞罗那。大流行病例从一开始直到6月18日,2020年,累积发病率与巴塞罗那城市的人口估计。MG发作的频率比前一年同期。结果:六十九(92 \ %)患者参与了这项研究。38(55 \ %)是男性,平均年龄69岁(IQR 49 {\ textendash} 77), 54(78 \ %)有广义和15(22 \ %)眼部毫克;55 (80 \ %)anti-AChR 4 (6 \ %) anti-MuSK和9(13 \ %)血清反应阴性的。58(84 \ %)患者接受免疫抑制剂。四个病人COVID-19,累积发病率是一般人群的类似于(5.8 vs 6.7 \ \ % %)。三(75 \ %)是男性,平均年龄61岁(范围26 {\ textendash} 88),所有与广义毫克,2 anti-AChR和2血清反应阴性的;3在强的松和1对咪唑硫嘌呤。 One was a healthcare worker and 1 resident of a nursing home. Three (75\%) patients required admission; all patients continued on MG therapy, and none received COVID-19 specific medications. One (25\%) patient died on day 2, and the other 3 were discharged after 8{\textendash}14 days. One patient had MG exacerbation 3 weeks later. Compared with MG patients without COVID-19 no differences were found on comorbidities, MG characteristics or treatments. Overall, 10 (14.5\%) patients developed MG exacerbation compared with 14 (20\%) of the previous year.Conclusions: The incidence of COVID-19 in MG patients is similar to that of the general population. The pandemic does not seem to increase the frequency of MG exacerbations.Disclosure: Diana Esteller Gauxax has nothing to disclose. Maria Sep{\'u}lveda has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Roche. Sara Llufriu has nothing to disclose. Mar Guasp has nothing to disclose. Mr. Cabrera Maqueda has nothing to disclose.{\'A}lvaro Carbayo has nothing to disclose. Montse Artola has nothing to disclose. Ana Hernando Andr{\'e}s has nothing to disclose. Dr. Graus has nothing to disclose. Dr. Blanco Morgado has nothing to disclose. Albert Saiz has nothing to disclose.}, issn = {0028-3878}, URL = {//www.ez-admanager.com/content/96/15_Supplement/4170}, eprint = {//www.ez-admanager.com/content}, journal = {Neurology} }