% 0期刊文章% B彼得。斯波恩% Marios-Nikos Psychogios %罗纳德·Straeter % Uta汉宁%一个Rene Chapot Jens Minnerup % %汉斯henk %一个依琳娜henk %阿斯特丽德克% Franziska多恩%一个马丁Wiesmann Omid Nikoubashman % %一个Georg棺材% Anushe韦伯% Jens Fiehler Gabriel Broocks % %一个亚历克斯Brehm %丹尼尔·凯瑟% Umut Yilmaz %一个沃尔夫冈Marik Andrea Morotti % % Ulf Jensen-Kondering理查德·Nolz % %迈克尔·布劳恩%一个奥利弗Beuing Stefan Schob % %一个弗里德里希Goetz % Johannes Trenkler % Bernd Turowski %一个克里斯蒂娜Wendl Markus Mohlenbruch % %一个彼得·施拉姆%帕特里夏·l·Musolino %莎拉李% Marc Schlamann % Andre Karch亚历山大Radbruch % %一个莫里茨Wildgruber妮可Rubsamen % %安德烈Kemmling %拯救孩子的调查人员% T栓子切除术临床扩散不匹配选择儿科患者卒中后6到24小时% B拯救孩子的分析研究% D R 10.1212 / WNL 2021%。00000000000188金宝慱官网下载11107 % J首页神经病学% P e343-e351 % V 96% N 3% X目的确定血栓切除术是安全的儿童后24小时内出现症状时选择临床赤字和梗塞之间的不匹配。方法的二次分析保存孩子的研究(2000年1月- 2018年12月)进行,包括所有儿科患者(< 18年)诊断为27例接受血管内再通动脉缺血性中风的欧洲和美国中风中心。患者包括如果他们有相关临床赤字和梗塞之间的不匹配。结果20个孩子年龄中位数为10.5(四分位范围(差)7 - 14.6)年。其中,7是男性(35%),从发病到血栓切除术的平均时间为9.8小时(IQR 7.8 - -16.2)。神经结果改进从儿科NIH卒中量表得分中值为12.0 (IQR 8.8 - -20.3) 2.0进入第七天(IQR 1.2 - -6.8)。改良Rankin规模(夫人)得分中位数为1.0(差0 - 1.6)3个月和0.0(差0 - 1.0)24个月。一个病人发达瞬态peri-interventional血管痉挛;没有观察到其他并发症。比较分数的分数夫人夫人的黎明和化解3试验显示更高比例的好的结果在儿童与成人人口研究。Conclusions Thrombectomy in pediatric ischemic stroke in an extended time window of up to 24 hours after onset of symptoms seems safe and neurologic outcomes are generally good if patients are selected by a mismatch between clinical deficit and infarct.Classification of Evidence This study provides Class IV evidence that for children with acute ischemic stroke with a mismatch between clinical deficit and infarct size, thrombectomy is safe.AIS=arterial ischemic stroke; ASPECTS=Alberta Stroke Program Early CT Score; DAWN=DWI or CTP Assessment with Clinical Mismatch in the Triage of Wake-Up and Late Presenting Strokes Undergoing Neurointervention with Trevo; DEFUSE 3=Endovascular Therapy Following Imaging Evaluation for Ischemic Stroke; eTICI=expanded Treatment in Cerebral Infarction; IQR=interquartile range; LVO=large vessel occlusion; mRS=modified Rankin Scale; PedNIHSS=Pediatric NIH Stroke Scale; PSOM=Pediatric Stroke Outcome Measure %U //www.ez-admanager.com/content/neurology/96/3/e343.full.pdf