TY - T1的临床结果的比较具有抑制受损后延伸1和5年战斗脑震荡JF -神经学乔-神经病学SP - e387 LP - - 10.1212 / WNL e398做。首页0000000000011089六世盟- 96 - 3 -克里斯汀·l . Mac唐纳德盟杰森理发师盟Jana帕特森AU - Ann m .约翰逊盟卡洛琳Parsey盟-贝弗利·斯科特盟杰西·r·范氏AU -南希·r·Temkin Y1 - 2021/01/19 UR - //www.ez-admanager.com/content/96/3/e387.abstract N2 -目的比较1年和5年临床结果在两组combat-deployed服务成员没有首页脑损伤的两组与战争脑震荡更好地理解长期临床结果轨迹。方法这个前瞻性、观察、纵向multicohort研究了4 combat-deployed组:控制没有头部受伤有或没有接触爆炸和爆炸引起的战斗脑震荡患者或钝的创伤。一年和5年的临床评估包括相同的电池神经行为,精神,和认知的结果。共有347人完成了评估的时间点。横向和纵向的比较评估。整体集团效应与等级回归建模为一个4-category变量调整人口因素使用双向的意义阈值为0.05,与事后图基p值计算的两两比较。结果重要组差异在两个战斗脑震荡组相比,在5年随访发现横向比较控制神经行为(神经行为评分量表——(NRS);科恩d,−1.10−1.40,置信区间(CIs)(−0.82−1.32)(−0.97−1.83)由集团)和精神领域(dsm - iv Clinician-Administered创伤后应激障碍量表(帽);科恩d,−0.91−1.19,独联体(−0.63−1.19)(−0.76−1.62)由集团)症状以最小的认知能力的差异。战斗脑震荡团体还显示从1 - 5年评估临床显著下降(66% - -76%神经行为评分量表;由集团)41% - -54%精神病的帽子。 Both control groups fared better but a subset also had clinically significant decline (37%–50% neurobehavioral NRS; 9%–25% psychiatric CAPS by group).Conclusions There was an evolution, not resolution, of symptoms from 1- to 5-year evaluation, challenging the assumption that chronic stages of concussive injury are relatively stable. Even some of the combat-deployed controls worsened. The evidence supports new considerations for chronic trajectories of concussion outcome in combat-deployed service members.CAPS=Clinician-Administered PTSD Scale for DSM-IV; CPT-II=Conner Continuous Performance Test II; CVLT-II=California Verbal Learning Test II; D-KEFS CWI=Delis–Kaplan Executive Function System Color-Word Interference Test; GOS-E=Glasgow Outcome Scale Extended; HIT=Headache Impact Test; MADRS=Montgomery-Åsberg Depression Rating Scale; MAST=Michigan Alcohol Screening Test; MIDAS=Migraine Disability Assessment; NOS-TBI=Neurologic Outcome Scale for TBI; NRS=Neurobehavioral Rating Scale–Revised; PTSD=posttraumatic stress disorder; TBI=traumatic brain injury ER -