TY -的T1 -编者注:COVID-19呈现与颅神经麻痹ophthalmoparesis JF -神经学乔-神经病学SP - 410 LP - 410 - 10.1212 / WNL。首页0000000000010407六世- 95 - 9盟- James e . Siegler三世AU -史蒂文Galetta A2 Galetta史蒂文Y1 - 2020/09/01 UR - //www.ez-admanager.com/content/9首页5/9/410.1.abstract N2 - Dinkin博士等人报道2例MRI证实的颅神经炎症的几天内系统性新型冠状病毒病的症状2019 (COVID-19)。病人SARS-CoV-2阳性,PCR从鼻拭子,和两人都用羟氯喹治疗(一个还有静脉注射免疫球蛋白),轻度短期改善。作者建议的炎症性颅神经病变可能是因为病毒后免疫相关反应。Machado博士怀疑颅神经病变可能导致直接的病毒入侵,鉴于其病毒后不久开始出现症状。如前所述Gutierrez-Ortiz et al。(Dinkin et al .,参考下面的2)发达的证据2例颅神经炎症和自身免疫性神经病变COVID-19后3 - 5天内出现症状。这些4例突出炎症颅神经病变的加速时间进程COVID-19系统性表现之后,这似乎比通常报道了更快速变异的格林-巴利综合征后其他传染性疾病。这些观察也支持,有一个无症状的阶段,这期间病毒感染免疫反应可能generated.Dr。Dinkin等人报道2例MRI证实的颅神经炎症的几天内系统性新型冠状病毒病症状的2019 (COVID-19)。病人SARS-CoV-2阳性,PCR从鼻拭子,和两人都用羟氯喹治疗(一个还有静脉注射免疫球蛋白),轻度短期改善。 The authors suggest the inflammatory cranial neuropathies could have been because of a postviral immune-related response. Dr. Machado wonders whether the cranial neuropathies could have resulted from direct viral invasion, given their onset shortly after the viral symptoms started. As noted by Gutiérrez-Ortiz et al. (Dinkin et al., reference 2 below) 2 patients developed evidence of cranial nerve inflammation and autoimmune neuropathy within 3–5 days of COVID-19 symptom onset. Each of these 4 cases highlight the accelerated time course of inflammatory cranial neuropathies after systemic manifestations of COVID-19, which seems to be more rapid than has been typically reported for variants of Guillain-Barré syndrome after other infectious illnesses. These observations may also support that there is an asymptomatic phase of this viral infection during which an immune response may be generated. ER -