PT -期刊文章盟亚当·哈里森盟史蒂文Broglio AU - r·戴维斯摩尔AU -安德鲁Lapointe AU -迈克尔·麦克雷博士TI -恢复配置文件后震荡中男运动员与神经退行性疾病的家族史:数据NCAA-DOD保健- 10.1212/01. wnl.0000580956.22284财团援助。a8 DP - 2019年10月01 TA -神经首页病学PG -向S14系列VI - 93 IP - 14补充1 4099 - //www.ez-admanager.com/content/93/14_Supplement_1/S13.2.short 4100 - //www.ez-admanager.com/content/93/14_Supplement_1/S13.2.full所以Neurology2019 10月01;93 AB -目标纵向评估复苏后震荡与fhNDD男运动员。背景的研究表明,神经退行性疾病的家族史(fhNDD)可能使一个运动员异常脑损伤后恢复。然而,没有人纵向脑震荡后复苏进行了评估与fhNDD男运动员。设计/方法的数据NCAA-DOD大联盟:脑震荡评估、研究和教育(保健)财团相比被用来男运动员(n = 51)和没有(n = 102)家族史的神经退行性疾病(帕金森病、阿尔茨海默氏症Non-Alzheimer的痴呆和轻度认知障碍)。所有运动员完成基线评估影响他们体育赛季开始之前。运动员脑震荡,持续被重新评估具有抑制受损,延伸24 - 48小时前un-restricted回到玩(RTP),又具有抑制受损。延伸6个月运动员没有fhNDD双匹配基于年龄、体重指数、运动范畴,脑震荡的历史。结果重复措施ANCOVA模型被用来评估具有抑制受损的计算,延伸性能在每个同时控制基线性能。一群×时间观察交互视觉记忆性能。 Post-hoc univariate analyses revealed that male athletes with fhNDD demonstrated significantly poorer visual memory performance 24–48 hours post-injury compared to controls (p ≤ 0.005). Additionally, we found a main effect of group for impulse control, indicating that male athletes with fhNDD demonstrated an increase number of impulse errors at all three post-injury evaluations (p ≤ 0.004). We did not to observe any other group differences (p’s > 0.05).Conclusions Our results suggest that male athletes with a family history of neurodegenerative disease may exhibit greater post-injury cognitive deficits compared to controls. Additionally, some deficits may persist for at least 6 months post-injury. Further research is warranted to investigate the interaction between family history of neurodegenerative disease and concussion.