@article {Baige675作者={法赫德贝格和马克·j·凯利和迈克尔·a·劳顿和克劳迪奥·Ruffmann米甲Rolinski和约翰内斯·c·克莱因和托马斯·巴伯和克里斯汀Lo和Yoav Ben-Shlomo该案和大卫和米歇尔·t·胡},title ={冲动控制障碍的帕金森病和RBD},体积={93}={7},页面= {e675——e687} = {2019}, doi = {10.1212 / WNL。出版商0000000000007942}= {Wolters Kluwer健康,公司代表美国神经病学学会},文摘={客观描述患病率、自然历史和风险因素控制冲动行为(学院)在帕金森病(PD)患者中首页,那些REM睡眠行为障碍(RBD),和控制。方法参与者与PD早期诊断(3.5年),那些RBD,控制临床表型和筛查银行独立委员会纵向(冲动的问卷帕金森{\ textquoteright}疾病)。ICB-positive个人被邀请半结构式访谈,重复1年后。ICB的严重性评估与帕金森{\ textquoteright}年代冲动控制规模。多个归责和回归模型来估计银行独立委员会患病率和关联。结果921例PD的基线数据,在18个月,768例和531例,包括在36个月,21 \ % 25 \ %筛查阳性银行独立委员会在每个访问。采访银行独立委员会屏幕{\ textendash}积极个人透露,10 \ %遇到正式标准冲动控制障碍(ICD),而33 \ % ICD亚综合征(ICB症状没有达到ICD)的正式的诊断标准。当这些数据是通过使用多个归责相结合,PD-ICB估计19.1 \ %的患病率(95 \ %置信区间10.1 {\ textendash} 28.2)。24 \ %的亚综合征病例随访,ICD了ICD的症状。PD-ICD与多巴胺受体激动剂使用,冷漠的运动并发症,但不是PD-RBD。ICD患病率RBD组(1 \ %)类似于控制(0.7 \ %)。Conclusions ICBs occur in 19.1\% of patients with early PD, many persisting or worsening over time. RBD is not associated with increased ICD risk. Psychosocial drivers, including mood and support networks, affect severity.CI=confidence interval; DA=dopamine agonist; DSM-5=Diagnostic and Statistical Manual of Mental Disorders, 5th edition; ICARUS=Impulse Control Disorders and the Association of Neuropsychiatric Symptoms, Cognition and Quality of Life in Parkinson Disease; ICB=impulse control behavior; ICD=impulse control disorder; LEDD=levodopa equivalent daily dose; MDS-UPDRS=Movement Disorder Society{\textendash}revised Unified Parkinson{\textquoteright}s Disease Rating Scale; PICS=Parkinson{\textquoteright}s Impulse-Control Scale; QUIP=Questionnaire for Impulse Control Disorders in Parkinson{\textquoteright}s Disease; QUIP-S=QUIP Short Form; RBD=REM sleep behavior disorder}, issn = {0028-3878}, URL = {//www.ez-admanager.com/content/93/7/e675}, eprint = {//www.ez-admanager.com/content/93/7/e675.full.pdf}, journal = {Neurology} }