% 0期刊文章%一个伊丽莎白·霍恩%莉莲火腿% Chuen-Yen刘斯坦利的拉波波特%约瑟夫·雪% % Avindra Nath %布莱恩史密斯% T对认知功能的影响很小,尽管高精神疾病的几率在治疗艾滋病毒(p4.9 - 008) % D J神经病学2019% % P p4.9 - 008 V % 92% N % X 15补充目的:评估精神疾病之间的关系和认知障碍患者的艾滋病毒感染对艺术> 12个月,而HIV-controls。首页背景:抑郁、焦虑、药物滥用和创伤后应激障碍是常见的艾滋病毒携带者(PLWH)。高发病率的这些条件与贫穷有关坚持艺术和疾病进展。这些条件的高患病率和协会与认知功能尚未研究病毒抑制PLWH相比,控制。设计/方法:受试者进行自然历史研究,包括一个全面的NP电池和一个详细的精神库存(客户端诊断问卷)屏幕的过去和当前的心理健康诊断和治疗。HIV阳性受试者对艺术至少1年。t是用来比较的结果。结果:年龄没有明显差异,种族之间的HIV阳性(n = 155)和艾滋病−组(n = 51)。有更多的女性艾滋病−组(49.0%比32.9%,p = 0.04)。HIV +组收到治疗抑郁显著多于对照组(分别为27.45%,50%,p < 0.01)。贝克抑郁量表二世HIV +的得分也明显高于相比,HIV−(分别平均3、7 p < 0.01)。 Additionally, treatment histories for anxiety and PTSD were significantly higher in the HIV+ group (p=0.01, p=0.03, respectively) as well as for drug abuse and alcohol abuse (p<0.01, p=0.01). However, there were no significant differences in rates of HAND or abnormal GDS between the HIV+ and HIV− groups (p=0.88, p=0.97, respectively).Conclusions: PLWH have higher rates of mental health and substance abuse disorders requiring treatment compared to HIV-controls. Despite this disproportionate burden of psychiatric disorders, the difference in cognitive function between the two groups remains minimal. Mental health disorders should be considered a clinically significant outcome that may be amenable to treatment even in those without cognitive impairment.Disclosure: Dr. Horne has nothing to disclose. Dr. Ham has nothing to disclose. Dr. Lau has nothing to disclose. Dr. Rapoport has nothing to disclose. Dr. Snow has nothing to disclose. Dr. Nath has received personal compensation in an editorial capacity for Practice Update Neurology. Dr. Smith has nothing to disclose. %U

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