TY - T1的早期预防性治疗减少了开发后慢性创伤后头痛的脑震荡JF -神经学乔-神经病学SP - S29 LP - S29做wnl.0000550646.79759 10.1212/01.。首页e1六世- 91 - 23补充1 AU -科伦伊恩盟Hoskin贾斯汀盟Al-Hasan Yazan AU - Zieman Glynnis AU - Cardenas哈维尔Y1 - 2018/12/04 UR - //www.ez-admanager.com/content/91/23_Supplement_1首页/S29.2.abstract N2 -背景脑震荡后头痛是常见的,潜在的衰弱,而持久的。目前没有创伤后头痛的治疗指南(甲状旁腺素)。本研究的目的是调查的影响发展的早期预防性药物治疗慢性创伤后头痛(cPTH)在青少年和成人脑震荡患者。方法回顾性登记病人患者人群的巴罗脑震荡和脑损伤中心(凤凰城,AZ)从之前的5年。13岁及以上男性和女性诊断为甲状旁腺素归因于轻微头部受伤基于ICHD2标准人头痛预防药物提供包括在内。患者分为3组:那些没有采取治疗(治疗),服用去甲替林(也),和那些服用托吡酯(上)。组分为那些发达cPTH和那些没有(ncPTH)。的平均时间从伤病开始治疗(说)天内进行了分析使用t和团体之间。结果一百二十例符合纳入标准的研究(治疗= 36,顶级= 46岁,也不是= 38)。总体而言,64年的120名患者遇到cPTH标准(53%)。SoT and development of cPTH is significant overall (35 vs 23, p< 0.001). SoT is significant for Untreated (NcPTH 14.4 vs cPTH 35.6, p = 0.001) and Top (NcPTH 23.9 vs cPTH 35.5, p = 0.002), but not for Nor (NcPTH 31.9 vs cPTH 34.0, p = 0.372). For NcPTH there is a significant difference between SoT for Untreated and Top (14.4 vs 23.9, p = 0.04) and Untreated vs Nor (14.4 vs 31.9, p = 0.002), but not Top and Nor (23.9 vs 31.9, p = 0.09). For cPTH there is no difference for SoT between groups.Conclusion Early intervention with nonpharmacologic treatments and topiramate is associated with reduced development of cPTH. ER -