PT -期刊文章盟德里克·c·梦露盟-大卫Keator AU -罗伯特Blumenfeld AU -詹姆斯·希克斯盟史蒂文·l·小TI -功能连通性变化与一个赛季head-to-ball影响接触的男性大学生足球运动员援助- 10.1212/01. wnl.0000550677.08469.57 DP - 2018 12月04 TA -神经病学PG - S14系列S15 VI - 91 IP - 23补充1 4099 - //www.ez-admanager.com/content/91/23_Supplement_1/S14.2.short 4100 - //www.ez-admanager.com/content/91/23_Supp首页lement_1/S14.2.full所以Neurology2018 04年12月;91 AB -目标Return-to-play协议可以通过更好的理解改善轻度创伤性脑损伤的生理效应(mTBI)。自主神经失调被认为构成的多维mTBI后症状和可能来自改变连接大脑的中央自主网络(可以)。了解损伤之间的关系,可以连接可能导致对mTBI有用的生物标志物。为此目的,本研究旨在建立正式关系non-symptomatic head-to-ball影响(“头文件”),能够连接在大学足球运动员。方法11男性全国大学生足球运动员训练监控员工在1季的头。十个男性全国大学生运动员(3越野和7高尔夫球手)作为控制。所有的参与者进行了静息状态功能磁共振成像和季后赛。二十roi选择基于以往涉及区域控制和自主功能的调制。图理论分析被用来探测网络体系结构和连接的变化。具体对比集中在预处理和季后赛的变化被解释为接触头的个体差异(p & lt; 0.05 uncorrected).Results Within the 20 node network, increases in headers were associated with reduced degree centrality of the left and right insular cortex and right putamen (p< 0.02), increased degree and betweenness centrality in the left anterior and right posterior Para hippocampal gyri (p< 0.03), and increased betweenness centrality in the anterior cingulate cortex (p = 0.006). Headers were also associated with reduced functional connectivity within the subnetwork including the anterior cingulate cortex (p = 0.0073), right hippocampus, left putamen, and left insular cortex (p< 0.04).Conclusion Highly skilled soccer players who sustained the greatest number of head impacts also experienced the greatest altered connectivity among regions associated with autonomic function. Future work to establish autonomic function as an injury biomarker should consider the importance of cumulative impact magnitudes.