TY - T1的多发性硬化症的患病率和特殊的特点,老年人(P2.386) JF -神经学乔-神经学六世- 90 - 15补充SP - P2.386盟给加西亚莫利纳AU -加布里埃尔·瓦莱罗能源洛佩兹盟安娜以斯帖Baidez格雷罗州盟-何塞·佩首页雷斯·迪亚兹盟Luna Fuentes鲁米非盟-何塞玛丽亚卡布瑞拉Maqueda AU - Rocio埃尔南德斯克莱尔盟酯卡伦Guarnizo盟——何塞台面式晶体管Lallana Y1 - 2018/04/10 UR - //www.ez-admanager.com/content/90/15_Supplement/P2.386.abstract N2 -目的:本研究的目的是审查患病率,演讲中,特殊的临床特点和认知障碍的患病率在晚发性多发性硬化症(lom)。背景:多发性硬化症(MS)通常20 - 40岁之间的首次亮相;然而,50岁后的第一个症状可能发生(归类为lom),和这个年龄段的特点可以不同于年轻的病人。设计/方法:回顾性研究450 MS患者建立包括根据难题或麦当劳标准,选择那些年龄超过50年,回顾他们的人口统计特征、首次发作症状,诊断延迟,残疾的诊断(eds)、发展指数(PI),疾病,认知障碍,发现在脑脊液和核磁共振的研究中,和治疗。结果:21 lom患者(4 7%),占总数的450 MS患者,诊断在1982年和2016年之间。15(71%)的女性和男性6例(29%)。在发病平均年龄是53 (SD±3、4)。最常见的第一个症状是电动机赤字(52%),其次是脑干疾病(24%),和感觉赤字(10%)。临床过程是在42%复发缓和(RR),在38%的主要进步(PP)和次要进步(SP)的19%。最初的eds得分是3分,7 (SD±1 8)。的意思是π是0,48。诊断延迟的意思是52个月。 The brain MRI has 3 nine lesions in 86%, and spine MRI has 3 three lesions in 52%. IgG oligoclonal bands were positive in 71% of patients in the CSF study. In addition 5 out of 21 (31%) patients had suffered a major depressive episode and 44% had cognitive impairment. In six cases there was a previous wrong diagnosis, being the most frequent the spondyloartrhitic cervical myelopathy.Conclusions: In our series the prevalence of LOMS is similar to other, the most common type is RR but PP is more frequent than in another younger groups, and the cognitive impairment is similar to general MS population.Disclosure: Dr. Valero López has nothing to disclose. Dr. Valero López has nothing to disclose. Dr. Baidez Guerrero has nothing to disclose. Dr. Diaz Perez has nothing to disclose. Dr. Fuentes Rumi has nothing to disclose. Dr. Cabrera Maqueda has nothing to disclose. Dr. Hernandez Clares has nothing to disclose. Dr. Carreon Guarnizo has nothing to disclose. Dr. Meca Lallana has nothing to disclose. ER -